ArticleThe journal of physiological sciences : JPS2011
Vascular adaptations to hypobaric hypoxic training in postmenopausal women.
Article in The journal of physiological sciences : JPS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effect of Exercise on Arterial Stiffness in Healthy Young, Middle-Aged and Older Women: A Systematic Review.Nutrients · 2023Pooled it
- The Methodological Quality of Studies Investigating the Acute Effects of Exercise During Hypoxia Over the Past 40 years: A Systematic Review.Frontiers in physiology · 2022Pooled it
- Effects of Different Intensities and Durations of Aerobic Exercise on Vascular Endothelial Function in Middle-Aged and Elderly People: A Meta-analysis.Frontiers in physiology · 2021Pooled it
- Effects of Exercise Training in Hypoxia Versus Normoxia on Vascular Health.Sports medicine (Auckland, N.Z.) · 2016Pooled it
- Trial
- Effect of normobaric hypoxic exercise on blood pressure in old individuals.European journal of applied physiology · 2021Trial
- Hypoxic Pilates Intervention for Obesity: A Randomized Controlled Trial.International journal of environmental research and public health · 2020Trial
- The effect of acute exercise in hypoxia on flow-mediated vasodilation.European journal of applied physiology · 2013Trial
- Leg vascular function with advancing age in men: the impact of physical activity and endurance exercise training.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- Inter-individual variation in SpOPhysiological reports · 2025Article
- Effects of regular exercise on vascular function with aging: Does sex matter?American journal of physiology. Heart and circulatory physiology · 2024Review
- Aging, aerobic exercise, and cardiovascular health: Barriers, alternative strategies and future directions.Experimental gerontology · 2023Review
- Hypoxic Therapy as a New Therapeutic Modality for Cardiovascular Benefit: A Mini Review.Reviews in cardiovascular medicine · 2022Review
- Therapeutic approach for digestive system cancers and potential implications of exercise under hypoxia condition: what little is known? a narrative review.Journal of cancer research and clinical oncology · 2022Review
- Effects of Interval Training Under Hypoxia on the Autonomic Nervous System and Arterial and Hemorheological Function in Healthy Women.International journal of women's health · 2022Article
- Does intermittent hypoxic exposure enhance the cardioprotective effect of exercise in an inactive population?Frontiers in physiology · 2022Article
- Mild Hypobaric Hypoxia Enhances Post-exercise Vascular Responses in Young Male Runners.Frontiers in physiology · 2019Article
- Limitation of Maximal Heart Rate in Hypoxia: Mechanisms and Clinical Importance.Frontiers in physiology · 2018Review
- Therapeutic Use of Exercising in Hypoxia: Promises and Limitations.Frontiers in physiology · 2016Article
- Hypoxic Conditioning as a New Therapeutic Modality.Frontiers in pediatrics · 2015Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to examine the effects of exercise training in hypoxia on arterial stiffness and flow-mediated vasodilation (FMD) in postmenopausal women. Sixteen postmenopausal women (56±1 years) were assigned to a normoxic exercise group (Normoxic group, n=8) or a hypoxic exercise group (Hypoxic group, n=8). The Hypoxic group performed exercise under hypobaric hypoxic conditions corresponding to 2000 m above sea level, and was exposed to these conditions for 2 h per session. Aquatic exercise was performed at an intensity of around 50% peak oxygen uptake for 30min, 4days per week, for 8 weeks. Arterial stiffness was assessed by brachial-ankle pulse wave velocity (baPWV), and FMD was evaluated by peak diameter of the popliteal artery during reactive hyperemia. After the 8 weeks of training, the Normoxic group showed no significant changes. In contrast, baPWV (P < 0.05) was significantly reduced and peak diameter (P<0.05) and %FMD (P<0.01) were significantly increased in the Hypoxic group after training. These results suggest that exercise training under mild intermittent hypoxic conditions could more effectively reduce arterial stiffness in postmenopausal women, compared with exercise training performed at the same relative intensity under normoxic conditions. Our data also indicate that hypoxic exercise training may induce vascular functional adaptation, for example an increase in FMD response. These findings therefore could have important implications for the development of a new effective exercise prescription program.
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