Evidence map›Paper›PMID 21181265›Full record

ReviewNeurochemical research2011

Remodeling of sphingolipids by plasma membrane associated enzymes.

Massimo Aureli, Nicoletta Loberto, Vanna Chigorno, Alessandro Prinetti, Sandro Sonnino

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurochemical research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Biochemical Characterization of theInternational journal of molecular sciences · 2018
    Article
  11. Article
  12. Glycosphingolipid-Protein Interaction in Signal Transduction.International journal of molecular sciences · 2016
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Massimo AureliCenter of Excellence on Neurodegenerative Diseases, Department of Medical Chemistry, Biochemistry and Biotechnology, University of Milan, Segrate, Italy.
Nicoletta Loberto
Vanna Chigorno
Alessandro Prinetti
Sandro Sonnino
University of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sphingolipid plasma membrane content and pattern is the result of several processes, among which the main, in term of quantity, are: neo-biosynthesis in endoplasmic reticulum and Golgi apparatus, membrane turnover with final catabolism in lysosomes and membrane shedding. In addition to this, past and recent data suggest that the head group of sphingolipids can be opportunely modified at the plasma membrane level, probably inside specific membrane lipid domains, by the action of enzymes involved in the sphingolipids metabolism, working directly at the cell surface. The number of membrane enzymes, hydrolases and transferases, acting on membrane sphingolipids is growing very rapidly. In this report we describe some properties of these enzymes.

Indexed as

AnimalsCell MembraneEndoplasmic ReticulumGlycoside HydrolasesGlycosyltransferasesGolgi ApparatusHumansLigasesLipid MetabolismMembrane LipidsPhosphotransferasesSphingolipidsGlycoside HydrolasesGlycosyltransferasesLigasesMembrane LipidsPhosphotransferasesSphingolipids

Identifiers

PMID21181265
OpenAlexW1998899460

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.