ArticleSao Paulo medical journal = Revista paulista de medicina2010
Use of albumin as a risk factor for hospital mortality among burn patients in Brazil: non-concurrent cohort study.
Article in Sao Paulo medical journal = Revista paulista de medicina, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Albumin in Burn Shock Resuscitation: A Meta-Analysis of Controlled Clinical Studies.Journal of burn care & research : official publication of the American Burn AssociationPooled it
- Quality indicators for hospital burn care: a scoping review.BMC health services research · 2024Article
- Plasma and dietary antioxidant status as cardiovascular disease risk factors: a review of human studies.Nutrients · 2013Review
- Economic evaluation of human albumin use in patients with nephrotic syndrome in four Brazilian public hospitals: pharmacoeconomic study.Sao Paulo medical journal = Revista paulista de medicinaArticle
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CONTEXT AND
objectiveamong burn patients, it is common to use colloidal substances under the justification that it is necessary to correct the oncotic pressure of the plasma, thereby reducing the edema in the burnt area and the hypotension. The aim here was to assess the risk of hospital mortality, comparing the use of albumin and crystalloid solutions for these patients. DESIGN AND
settingnon-concurrent historical cohort study at Faculdade de Medicina de Marília; within the Postgraduate program on Internal and Therapeutic Medicine, Universidade Federal de São Paulo; and at the Brazilian Cochrane Center.
methodsburn patients hospitalized between 2000 and 2001, with registration in the Hospital Information System, who received albumin, were compared with those who received other types of volume replacement. The primary outcome was the hospital mortality rate. The data were collected from files within the Datasus software.
results39,684 patients were included: 24,116 patients with moderate burns and 15,566 patients with major burns. Among the men treated with albumin, the odds ratio for the risk of death was 20.58 (95% confidence interval, CI: 11.28-37.54) for moderate burns and 6.24 (CI 5.22-7.45) for major burns. Among the women, this risk was 40.97 for moderate burns (CI 21.71-77.30) and 7.35 for major burns (CI 5.99-9.01). The strength of the association between the use of albumin and the risk of death was maintained for the other characteristics studied, with statistical significance.
conclusionthe use of albumin among patients with moderate and major burns was associated with considerably increased mortality.
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