Evidence map›Paper›PMID 21180613›Full record

ArticleTherapeutic advances in gastroenterology2010

The bacterial pathogenesis and treatment of pouchitis.

S D McLaughlin, S K Clark, P P Tekkis, R J Nicholls, P J Ciclitira

Open access · greenAbstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
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  9. Review
  10. Alterations in the Abundance and Co-occurrence ofFrontiers in cellular and infection microbiology · 2018
    Article
  11. Article
  12. Review
  13. Fecal microbiota in pouchitis and ulcerative colitis.World journal of gastroenterology · 2016
    Article
  14. Review article: the pathogenesis of pouchitis.Alimentary pharmacology & therapeutics · 2016
    Review
  15. Article
  16. Article
  17. Article
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  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

S D McLaughlinChelsea and Westminster Hospital, London SW10 9NH, UK.
S K Clark
P P Tekkis
R J Nicholls
P J Ciclitira
Imperial College London · GBChelsea and Westminster Hospital · GBKing's College London · GBSt Mark's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis is the operation of choice for patients with ulcerative colitis. Pouchitis is the most common cause of pouch dysfunction. Although the pathogenesis of this disease is not well understood, bacteria have been implicated in the disease process. Numerous bacterial studies have been reported over the last 25 years with few unifying findings. In addition, many different treatments for pouchitis have been reported with varying results. Antibiotic treatment remains the most studied and is the mainstay of treatment. In this article we review the aetiology of pouchitis and the evidenced-based treatment options.

Indexed as

dysbiosisfamilial adenomatous polyposisileal pouch-anal anastomosisinflammatory bowel diseasepouchitisrestorative proctocolectomyulcerative colitis

Identifiers

PMID21180613
PMCPMC3002591
OpenAlexW2075660718

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.