Evidence map›Paper›PMID 21180401›Full record

ArticleJALA (Charlottesville, Va.)2010

Electrothermal Fluid Manipulation of High-Conductivity Samples for Laboratory Automation Applications.

Mandy L Y Sin, Vincent Gau, Joseph C Liao, Pak Kin Wong

Abstract read
In one paragraph

Article in JALA (Charlottesville, Va.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Long-range electrothermal fluid motion in microfluidic systems.International journal of heat and mass transfer · 2016
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Development of a 3D graphene electrode dielectrophoretic device.Journal of visualized experiments : JoVE · 2014
    Article
  17. Article
  18. A Universal Electrode Approach for Automated Electrochemical Molecular Analyses.Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems · 2013
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mandy L Y SinDepartment of Aerospace and Mechanical Engineering, University of Arizona, PO Box 210119, Tucson, AZ 85721 USA.
Vincent Gau
Joseph C Liao
Pak Kin Wong
University of Arizona · USGeneFluidics (United States) · USStanford University · US

Funding

An Integrated Diagnostic Biochip for Point of Care Pathogen IdentificationU01AI082457 · NIAID · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI LIAO, JOSEPH C · 2009 to 2013
$3.7M
An Integrated Diagnostic System for Rapid Antimicrobial Susceptibility TestingR44AI088756 · NIAID · GENEFLUIDICS, INC. · PI GAU, VINCENT JEN-JR · 2012 to 2014
$3.0M
Rapid Antimicrobial Susceptibility Test Cartridge for Resource-Limited SettingsR43AI088756 · NIAID · GENEFLUIDICS, INC. · PI GAU, VINCENT JEN-JR · 2010 to 2011
$700k
NIAID NIH HHS R43 AI088756NIAID NIH HHS R44 AI088756NIAID NIH HHS U01 AI082457
6 · The paper itself

Abstract

Electrothermal flow is a promising technique in microfluidic manipulation toward laboratory automation applications, such as clinical diagnostics and high throughput drug screening. Despite the potential of electrothermal flow in biomedical applications, relative little is known about electrothermal manipulation of highly conductive samples, such as physiological fluids and buffer solutions. In this study, the characteristics and challenges of electrothermal manipulation of fluid samples with different conductivities were investigated systematically. Electrothermal flow was shown to create fluid motion for samples with a wide range of conductivity when the driving frequency was above 100 kHz. For samples with low conductivities (below 1 S/m), the characteristics of the electrothermal fluid motions were in quantitative agreement with the theory. For samples with high conductivities (above 1 S/m), the fluid motion appeared to deviate from the model as a result of potential electrochemical reactions and other electrothermal effects. These effects should be taken into consideration for electrothermal manipulation of biological samples with high conductivities. This study will provide insights in designing microfluidic devices for electrokinetic manipulation of biological samples toward laboratory automation applications in the future.

Identifiers

PMID21180401
PMCPMC3003926
OpenAlexW2118684376

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.