ArticleTherapeutic advances in neurological disorders2010
An update on the treatment of Sydenham's chorea: the evidence for established and evolving interventions.
Article in Therapeutic advances in neurological disorders, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.
- Treatment of Secondary Chorea: A Review of the Current Literature.Tremor and other hyperkinetic movements (New York, N.Y.) · 2020Pooled it
- Children With Sydenham Chorea and Psychiatric Disorders Had Variable Long-Term Outcomes and Required Multidisciplinary Management.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Sydenham's chorea in a 16-year-old female from Bhutan: A case report.Clinical case reports · 2024Article
- Chorea as the only presenting clinical feature of rheumatic fever: a case report.Annals of medicine and surgery (2012) · 2024Article
- Childhood/adolescent Sydenham's chorea in the UK and Ireland: a BPSU/CAPSS surveillance study.Archives of disease in childhood · 2023Article
- Corticosteroid Treatment in Sydenham Chorea: A 27-Year Tertiary Referral Center Experience.Children (Basel, Switzerland) · 2023Article
- Rare Recurrence of Sydenham Chorea in an Adult: A Case Report.International medical case reports journal · 2023Article
- Psychopathological Impact in Patients with History of Rheumatic Fever with or without Sydenham's Chorea: A Multicenter Prospective Study.International journal of environmental research and public health · 2022Article
- Sydenham's Chorea as the First Manifestation of Rheumatic Fever in Two Boys.Mediterranean journal of rheumatology · 2021Article
- Uncontrollable movements of right upper and lower extremities in a child: A diagnostic puzzle.Journal of the American College of Emergency Physicians open · 2021Article
- Chorea as the presenting feature of acute rheumatic fever in childhood; case reports from a low-prevalence European setting.BMC infectious diseases · 2021Article
- Inflammation, Obsessive-Compulsive Disorder, and Related Disorders.Current topics in behavioral neurosciences · 2021Article
- Article
- An Update on the Treatment of Chorea.Current treatment options in neurology · 2018Review
- Group A Streptococcus, Acute Rheumatic Fever and Rheumatic Heart Disease: Epidemiology and Clinical Considerations.Current treatment options in cardiovascular medicine · 2017 · on this mapReview
- [Exceptionally good response to sodium valproate in patients with recurrent Sydenham's chorea].The Pan African medical journal · 2017Article
- Treatment of Sydenham's Chorea: A Review of the Current Evidence.Tremor and other hyperkinetic movements (New York, N.Y.) · 2017Review
- Successful treatment of Sydenham's chorea with intravenous immunoglobulin.BMJ case reports · 2016Article
- Neuropsychological manifestations in children with Sydenham's chorea after adjunct intravenous immunoglobulin and standard treatment.Metabolic brain disease · 2016Article
- The Diagnosis and Treatment of Autoimmune Encephalitis.Journal of clinical neurology (Seoul, Korea) · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over 320 years after Thomas Sydenham described the condition labelled Sydenham's chorea, it remains poorly understood. The disorder is an antineuronal antibody-mediated neuropsychiatric disorder caused by a poststreptococcal, autoimmune condition affecting control of movement, mood, behaviour and potentially the heart. The treatment remains empirical, and is less than optimal. There are few large clinically controlled trials. Recommendations for optimal management remain inconsistent and are hampered by the side effects from pharmacotherapy. Care for patients should be targeted at primary treatment (penicillin and bed rest), secondary palliation (symptomatic medication) and supportive (social) care. Small studies have demonstrated trends to support the use of immunoglobulins and steroids as therapeutic interventions for children affected by Sydenham's chorea.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.