ArticleTherapeutic advances in neurological disorders2010
Treatment options in trigeminal neuralgia.
Article in Therapeutic advances in neurological disorders, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 2 syntheses or guidelines pooled it, 207 citations in OpenAlex.
- Evaluation of Carbamazepine and Gabapentin's Safety and Efficacy in Trigeminal Neuralgia Treatment: A Systematic Review and Meta-Analysis.Combinatorial chemistry & high throughput screening · 2026Pooled it
- Interventions for Refractory Trigeminal Neuralgia: A Bayesian Mixed Treatment Comparison Network Meta-Analysis of Randomized Controlled Clinical Trials.Clinical drug investigation · 2017Pooled it
- Trial
- Trigger zones in trigeminal neuralgia: clinical features, pathophysiological mechanisms, and therapeutic strategies.Frontiers in neurology · 2026Review
- Precision and Relief: The Ginwala Technique in Trigeminal Neuralgia Treatment.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- The Impact of Microvascular Decompression on Pain Management in Trigeminal Neuralgia: Clinical Insights.Cureus · 2024Article
- Botulinum Toxin Type A in Trigeminal Neuralgia Treatment: A Case Series and Literature Review.Cureus · 2024Article
- Chiari malformation and its influence on trigeminal neuralgia: a systematic review.Annals of medicine and surgery (2012) · 2024Review
- A Retrospective Analysis of Medical Management Strategies for Trigeminal Neuralgia: An Institutional Review.Cureus · 2024Article
- Multimodality Treatment of Trigeminal Neuralgia: An Institutional Experience.Asian journal of neurosurgery · 2024Article
- Comparative Assessment of the Effectiveness of Carbamazepine and Baclofen in the Management of Trigeminal Neuralgia.Journal of pharmacy & bioallied sciences · 2024Article
- A prospective cohort study on perioperative percutaneous balloon compression for trigeminal neuralgia: safety and efficacy analysis.Neurosurgical review · 2024Article
- Fenestrated Aneurysm Clip Trigeminal Decompression after CyberKnife Treatment Failure.Journal of neurological surgery. Part B, Skull base · 2024Article
- Article
- Article
- Sex-Specific Pain Outcomes Following Microvascular Decompression for Trigeminal Neuralgia.World neurosurgery · 2023Article
- Absent Meckel's cave as a possible cause of trigeminal neuralgia: A case report.Radiology case reports · 2023Article
- Magnetic Resonance-guided Focused Ultrasound thalamotomy for refractory neuropathic pain: a systematic review and critical appraisal of current knowledge.Therapeutic advances in neurological disorders · 2023Review
- Electrophysiological and computational analysis of CaMolecular brain · 2022Article
- Ashi Scalp Acupuncture in the Treatment of Secondary Trigeminal Neuralgia Induced by Multiple Sclerosis: A Case Report.Medicines (Basel, Switzerland) · 2022Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of trigeminal neuralgia (TN) is 4.3 per 100,000 persons per year, with a slightly higher incidence for women (5.9/100,000) compared with men (3.4/100,000). There is a lack of certainty regarding the aetiology and pathophysiology of TN. The treatment of TN can be very challenging despite the numerous options patients and physicians can choose from. This multitude of treatment options poses the question as to which treatment fits which patient best. The preferred medical treatment for TN consists of anticonvulsant drugs, muscle relaxants and neuroleptic agents. Large-scale placebo-controlled clinical trials are scarce. For patients refractory to medical therapy, Gasserian ganglion percutaneous techniques, gamma knife surgery and microvascular decompression are the most promising invasive treatment options.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.