ArticleScientia pharmaceutica
New 4-thiazolidinones of nicotinic acid with 2-Amino-6-methylbenzothiazole and their biological activity.
Article in Scientia pharmaceutica. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Thiadiazole and Thiazole Derivatives as Potential Antimicrobial Agents.Mini reviews in medicinal chemistry · 2024Review
- Design, molecular docking analysis of an anti-inflammatory drug, computational analysis and intermolecular interactions energy studies of 1-benzothiophene-2-carboxylic acid.Computational biology and chemistry · 2020Article
- A comprehensive review on biological activities of oxazole derivatives.BMC chemistry · 2019Review
- Synthesis of a series of benzothiazole amide derivatives and their biological evaluation as potent hemostatic agents.RSC advances · 2018Article
- Analytical Techniques Used to Detect DNA Binding Modes of Ruthenium(II) Complexes with Extended Phenanthroline Ring.Journal of fluorescence · 2017Review
- [(1,3-Benzothia-zol-2-yl)amino-carbon-yl]meth-yl piperidine-1-carbodithio-ate monohydrate.Acta crystallographica. Section E, Structure reports online · 2011Article
- N-[2-(4-Chloro-phen-yl)-5-methyl-4-oxo-1,3-thia-zolidin-3-yl]pyridine-3-carboxamide.Acta crystallographica. Section E, Structure reports online · 2011Article
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Authors and funding
2 authors.
Funding
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Abstract
The title compounds 6aâj, 2-[(6-methyl-1,3-benzothiazol-2-yl)amino]-N-[2-(substituted phenyl/furan-2-yl)-4-oxo-1,3-thiazolidin-3-yl]nicotinamides, were prepared from 2-chloropyridine-3-carboxylic acid (1) and 2-amino-6-methyl-benzothiazole (2) by known methods. All the compounds have been established by IR, (1)H NMR, (13)C NMR and elemental analyses. The in vitro antimicrobial screening of the compounds were carried out against two Gram positive (S. aureus, S. pyogenes), two Gram negative (E. coli, P. aeruginosa) bacteria and three fungal species (C. albicans, A. niger, A. clavatus) using the broth microdilution method. Some of the compounds are comparable with standard drugs.
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Registered trials
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