ArticleClinical ophthalmology (Auckland, N.Z.)2010
Association between assisted reproductive technology and advanced retinopathy of prematurity.
Article in Clinical ophthalmology (Auckland, N.Z.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- The Risk of Retinopathy of Prematurity in the Infants following Assisted Reproductive Technology: A Meta-Analysis.BioMed research international · 2019Pooled it
- Incidence and risk factors of retinopathy of prematurity in artificial reproductive technology conceived preterm infants in China.International journal of retina and vitreous · 2026Article
- Perinatal and neonatal risk factors for retinopathy of prematurity in very low birthweight, very preterm twins: a population-based study.Eye (London, England) · 2024Observational
- Retinopathy of prematurity: contribution of inflammatory and genetic factors.Molecular and cellular biochemistry · 2022Review
- Retinopathy of Prematurity and Assisted Reproductive Technology: Is There an Association?Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Artificial Reproductive Technology - A Risk Factor for Retinopathy of Prematurity.Open access Macedonian journal of medical sciences · 2018Review
- Genomics in the neonatal nursery: Focus on ROP.Seminars in perinatology · 2015Review
- Incidence and risk factors for retinopathy of prematurity in multiple gestations: a Chinese population study.Medicine · 2015Article
- Risk Factors for Retinopathy of Prematurity in Preterm Infants in Kerman, Iran.Journal of ophthalmic & vision researchArticle
- Retinopathy of prematurity: a review of risk factors and their clinical significance.Survey of ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 1 country.
Funding
Abstract
purposeTo investigate the associations between assisted reproductive technology (ART) and severe retinopathy of prematurity (ROP) requiring treatment.
methodsRetrospective analyses of inborn preterm infants screened for severe ROP at the Weill Cornell Medical Center Neonatal Intensive Care Unit at the New York-Presbyterian Hospital by single factor logistic regression and multifactor models.
resultsOf 399 ethnically diverse infants, 253 were conceived naturally and 146 by ART. Eight (3.16%) patients conceived naturally, and 11 (7.53%) with ART required laser treatment. In multifactor analyses, significant risks for severe ROP requiring treatment included both gestational age (odds ratio [OR] 0.34; 95% confidence interval [CI] 0.23-0.52; P < 0.001) and ART ([OR] 4.70; [CI], 1.52-4.57; P = 0.007).
conclusionsART is associated with severe ROP requiring treatment in this cohort. This is the first report that demonstrates a statistically significant association between ART and severe ROP requiring treatment in infants in the US.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.