ReviewNature reviews. Immunology2011
Imaging techniques for assaying lymphocyte activation in action.
Review in Nature reviews. Immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed.
- Polarized hyperspectral and polarized light microscopic imaging for enhanced visualization of white blood cells.Journal of biomedical optics · 2026Article
- Planar Immunological Synapses Formed by Human CD4 T Cells as In Vitro System to Study Actin and Tubulin Dynamics Through TIRF Microscopy.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Coupling Molecular and Cellular Dynamics in a Large-Scale Monte Carlo Simulation.International journal of molecular sciences · 2025Article
- Super-resolution imaging of T lymphocyte activation reveals chromatin decondensation and disrupted nuclear envelope.Communications biology · 2024Article
- A roadmap for translational cancer glycoimmunology at single cell resolution.Journal of experimental & clinical cancer research : CR · 2022Review
- Disc Large Homolog 1 Is Critical for Early T Cell Receptor Micro Cluster Formation and Activation in Human T Cells.Vaccines · 2021Article
- Three-Dimensional Single Molecule Localization Microscopy Reveals the Topography of the Immunological Synapse at Isotropic Precision below 15 nm.Nano letters · 2021Article
- Bioengineering tools for probing intracellular events in T lymphocytes.WIREs mechanisms of disease · 2021Review
- Adhering interacting cells to two opposing coverslips allows super-resolution imaging of cell-cell interfaces.Communications biology · 2021Article
- Cytosolic delivery of membrane-penetrating QDs into T cell lymphocytes: implications in immunotherapy and drug delivery.Nanoscale · 2021Article
- Spectral Analysis of ATP-Dependent Mechanical Vibrations in T Cells.Frontiers in cell and developmental biology · 2021Article
- Capturing T Lymphocytes' Dynamic Interactions With Human Neural Cells Using Time-Lapse Microscopy.Frontiers in immunology · 2021Article
- Article
- Considerations of Antibody Geometric Constraints on NK Cell Antibody Dependent Cellular Cytotoxicity.Frontiers in immunology · 2020Review
- T Cell Reprogramming Against Cancer.Methods in molecular biology (Clifton, N.J.) · 2020Review
- Rapid Morphological and Cytoskeletal Response to Microgravity in Human Primary Macrophages.International journal of molecular sciences · 2019Article
- Interfacial actin protrusions mechanically enhance killing by cytotoxic T cells.Science immunology · 2019Article
- Investigating the aetiology of adverse events following HPV vaccination with systems vaccinology.Cellular and molecular life sciences : CMLS · 2019Review
- TCRs are randomly distributed on the plasma membrane of resting antigen-experienced T cells.Nature immunology · 2018Article
- Gp41 dynamically interacts with the TCR in the immune synapse and promotes early T cell activation.Scientific reports · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Imaging techniques have greatly improved our understanding of lymphocyte activation. Technical advances in spatial and temporal resolution and new labelling tools have enabled researchers to directly observe the activation process. Consequently, research using imaging approaches to study lymphocyte activation has expanded, providing an unprecedented level of cellular and molecular detail in the field. As a result, certain models of lymphocyte activation have been verified, others have been revised and yet others have been replaced with new concepts. In this article, we review the current imaging techniques that are used to assess lymphocyte activation in different contexts, from whole animals to single molecules, and discuss the advantages and potential limitations of these methods.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.