ArticleVirulence
Crowd control: Bacillus anthracis and quorum sensing.
Article in Virulence. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 6 citations in OpenAlex.
- luxS in bacteria isolated from 25- to 40-million-year-old amber.FEMS microbiology letters · 2014Article
Corrections and comments
- Comment on
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In 1965, Dr. Alexander Tomasz identified a critical component of the DNA uptake mechanism used by competent Streptococcus pneumoniae: the pneumococci secrete a polypeptide that induces the expression of proteins to allow foreign DNA to pass through the bacterium's cell wall. This hormone-like substance was the first of numerous "quorum-sensing" factors that have since been identified in many microbial processes. Detailed insights into the molecular mechanisms of quorum-sensing are now emerging, owing largely to studies focusing on the ability of marine organisms like Vibrio fischeri and Vibrio harveyi to produce light at high cell densities. The complexities of bioluminescence induction, and indeed that of an ever increasing group of other quorum-sensing phenotypes, show that such signaling pathways are not just an interesting phenomenon but rather represent a widespread mechanism by which bacterial populations can communicate, coordinate behavior and act in a cooperative manner in the environment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.