ArticleClinical and vaccine immunology : CVI2011
Evaluation of Salmonella-vectored Campylobacter peptide epitopes for reduction of Campylobacter jejuni in broiler chickens.
Article in Clinical and vaccine immunology : CVI, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 75 citations in OpenAlex.
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- A Comprehensive Review on Bacterial Vaccines Combating Antimicrobial Resistance in Poultry.Vaccines · 2023Review
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- Live-Attenuated Oral Vaccines to ReduceVaccines · 2022Article
- Stable Recombinant-Gene Expression from aApplied and environmental microbiology · 2021Article
- A Systematic Review ofMicroorganisms · 2021Review
- Approaches to prevent and control Campylobacter spp. colonization in broiler chickens: a review.Environmental science and pollution research international · 2021Review
- Lactic Acid Bacteria - A Promising Tool for Controlling ChickenFrontiers in microbiology · 2021Review
- Article
- Live Bacterial Prophylactics in Modern Poultry.Frontiers in veterinary science · 2020Review
- Potential for Prebiotics as Feed Additives to Limit FoodborneFrontiers in microbiology · 2019Review
- Coadministration of the Campylobacter jejuni N-Glycan-Based Vaccine with Probiotics Improves Vaccine Performance in Broiler Chickens.Applied and environmental microbiology · 2017Article
- B lymphocytes play a limited role in clearance of Campylobacter jejuni from the chicken intestinal tract.Scientific reports · 2017Article
- Current and Potential Treatments for ReducingFrontiers in microbiology · 2017Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Campylobacter is a leading cause of bacterial gastroenteritis in humans and is often linked to contaminated poultry products. Live Salmonella vectors expressing three linear peptide epitopes from Campylobacter proteins Cj0113 (Omp18/CjaD), Cj0982c (CjaA), and Cj0420 (ACE393) were administered to chicks by oral gavage on the day of hatch, and the chicks were challenged with Campylobacter jejuni on day 21. All three candidate vaccines produced consistent humoral immune responses with high levels of serum IgG and mucosal secretory IgA (sIgA), with the best response from the Cj0113 peptide-expressing vector. Campylobacter challenge following vaccination of three candidate vaccine groups decreased Campylobacter recovery from the ileum compared to that for controls on day 32. The Cj0113 peptide-expressing vector reduced Campylobacter to below detectable levels. The Salmonella-vectored Cj0113 subunit vaccine appears to be an excellent candidate for further evaluation as a tool for the reduction of Campylobacter in poultry for improved food safety.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.