Evidence map›Paper›PMID 21177884›Full record

ReviewAmerican journal of respiratory and critical care medicine2011

Novel developments in the epidemic of human immunodeficiency virus and tuberculosis coinfection.

Asha Anandaiah, Keertan Dheda, Joseph Keane, Henry Koziel, David A J Moore, Naimish R Patel

Abstract readReview
In one paragraph

Review in American journal of respiratory and critical care medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Autophagy in Mycobacterium tuberculosis and HIV infections.Frontiers in cellular and infection microbiology · 2015
    Review
  6. Cost utility of lateral-flow urine lipoarabinomannan for tuberculosis diagnosis in HIV-infected African adults.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2013
    Article
  7. Article
  8. Article
  9. Article
  10. Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases.American journal of respiratory and critical care medicine · 2012
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Asha AnandaiahDivision of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA.
Keertan Dheda
Joseph Keane
Henry Koziel
David A J Moore
Naimish R Patel
Beth Israel Deaconess Medical Center · USLondon School of Hygiene & Tropical Medicine · GBTrinity College Dublin · IEUniversity of Cape Town · ZA

Funding

ALVEOLAR MACROPHAGE INNATE IMMUNE FUNCTION IN HIVR01HL063655 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KOZIEL, HENRY · 2000 to 2010
$4.1M
TRAINING GRANT IN LUNG CELL &MOLECULAR BIOLOGYT32HL007874 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MEDOFF, BENJAMIN DAVID · 1997 to 2011
$4.1M
Lung macrophage innate receptor response to MTb in HIVK08AI064014 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI PATEL, NAIMISH RAMESH · 2005 to 2009
$596k
NHLBI NIH HHS R01 HL063655NHLBI NIH HHS T32-HL007874NIAID NIH HHS NIH K08AI064014
6 · The paper itself

Abstract

Tuberculosis (TB) disease remains one of the highest causes of mortality in HIV-infected individuals, and HIV-TB coinfection continues to grow at alarming rates, especially in sub-Saharan Africa. Surprisingly, a number of important areas regarding coinfection remain unclear. For example, increased risk of TB disease begins early in the course of HIV infection; however, the mechanism by which HIV increases this risk is not well understood. In addition, there is lack of consensus on the optimal way to diagnose latent TB infection and to manage active disease in those who are HIV infected. Furthermore, effective point-of-care testing for TB disease remains elusive. This review discusses key areas in the epidemiology, pathogenesis, diagnosis, and management of active and latent TB in those infected with HIV, focusing attention on issues related to high- and low-burden areas. Particular emphasis is placed on controversial areas where there are gaps in knowledge and on future directions of study.

Indexed as

AIDS-Related Opportunistic InfectionsAnti-HIV AgentsAntitubercular AgentsDrug InteractionsHumansLatent TuberculosisMycobacterium tuberculosisPrevalenceRifamycinsTuberculosis, PulmonaryAnti-HIV AgentsAntitubercular AgentsRifamycins

Identifiers

PMID21177884
PMCPMC3086746
OpenAlexW2132628905

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.