ArticleThe Plant cell2010
miR156-targeted and nontargeted SBP-box transcription factors act in concert to secure male fertility in Arabidopsis.
Article in The Plant cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 208 papers, 1 of them a synthesis that pooled it.
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Who cites it
208 citing papers in PubMed, 1 synthesis or guideline pooled it, 375 citations in OpenAlex.
- What Do We Know about Barley miRNAs?International journal of molecular sciences · 2022Pooled it
- Advances in the Functions and Molecular Mechanisms of SPL Transcription Factors in Plant Flower Development.Plants (Basel, Switzerland) · 2026Review
- Transcriptome analysis of a spontaneous male-sterile mutant in Betula platyphylla and functional characterization of the key gene BpSPL2 in regulating inflorescence development.Plant cell reports · 2026Article
- Integrative Hormone Metabolomic, Transcriptomic, and miRNA Sequencing Analyses Reveal Brassinosteroid-Mediated Sex Differentiation in Walnut Flower Buds.Plants (Basel, Switzerland) · 2026Article
- A novel CsbZIP26-CsSEP4-CsSPL18 regulatory module governs gynostemium morphology and floral architecture inHorticulture research · 2026Article
- Convergent evolution of sex chromosomes in two palm species, Phoenix dactylifera and Kerriodoxa elegans.Annals of botany · 2025Article
- MicroRNA156-SPL13B Module Induces Parthenocarpy Through the Gibberellin Pathway.Plant biotechnology journal · 2025Article
- Arabidopsis thaliana iron superoxide dismutase FeSOD1 protects ARGONAUTE 1 in a copper-dependent manner.Journal of experimental botany · 2025Article
- miR156-SPLs module regulates flowering and controls plant height by modulating gibberellin biosynthesis in citrus.Plant biotechnology journal · 2025Article
- Recent advances in improving yield and immunity through transcription factor engineering.Journal of integrative plant biology · 2025Review
- Genome-Wide Identification ofInternational journal of molecular sciences · 2025Article
- Article
- Functional Characterization ofPlants (Basel, Switzerland) · 2025Article
- An organ-specific transcriptome atlas of Curcuma wenyujin: MicroRNAs, phasiRNAs, and metabolic pathways.The plant genome · 2025Article
- Overexpression ofInternational journal of molecular sciences · 2025Article
- Non-coding RNAs and their role in plants: prospective omics-tools for improving growth, development and stress tolerance in field crops.Molecular biology reports · 2025Review
- Phylogenetic and Expression Analysis of SBP-Box Gene Family to Enhance Environmental Resilience and Productivity inPlants (Basel, Switzerland) · 2025Article
- Identification and expression analysis of the SPL gene family during flower bud differentiation in Rhododendron molle.Genes & genomics · 2025Article
- Global identification and regulatory network analysis reveal the significant roles of lncRNAs during anther and pollen development in Arabidopsis.Plant cell reports · 2025Article
- Transcriptional regulation of miR528-PPO module by miR156 targeted SPLs orchestrates chilling response in banana.Molecular horticulture · 2025Article
148 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The SBP-box transcription factor SQUAMOSA PROMOTER BINDING PROTEIN-LIKE8 (SPL8) is required for proper development of sporogenic tissues in Arabidopsis thaliana. Here, we show that the semisterile phenotype of SPL8 loss-of-function mutants is due to partial functional redundancy with several other members of the Arabidopsis SPL gene family. In contrast with SPL8, the transcripts of these latter SPL genes are all targeted by miR156/7. Whereas the introduction of single miR156/7-resistant SPL transgenes could only partially restore spl8 mutant fertility, constitutive overexpression of miR156 in an spl8 mutant background resulted in fully sterile plants. Histological analysis of the anthers of such sterile plants revealed an almost complete absence of sporogenous and anther wall tissue differentiation, a phenotype similar to that reported for sporocyteless/nozzle (spl/nzz) mutant anthers. Expression studies indicated a functional requirement for miR156/7-targeted SPL genes limited to early anther development. Accordingly, several miR156/7-encoding loci were found expressed in anther tissues at later stages of development. We conclude that fully fertile Arabidopsis flowers require the action of multiple miR156/7-targeted SPL genes in concert with SPL8. Either together with SPL/NZZ or independently, these SPL genes act to regulate genes mediating cell division, differentiation, and specification early in anther development. Furthermore, SPL8 in particular may be required to secure fertility of the very first flowers when floral transition-related miR156/7 levels might not have sufficiently declined.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.