ArticleThe Plant cell2010
Serine protease inhibitors specifically defend Solanum nigrum against generalist herbivores but do not influence plant growth and development.
Article in The Plant cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 104 citations in OpenAlex.
- An efficient system for plastid transformation in an edible medicinal herb.Transgenic research · 2025Article
- Protein Dynamics in Plant Immunity: Insights into Plant-Pest Interactions.International journal of molecular sciences · 2024Review
- Overexpression ofPlants (Basel, Switzerland) · 2024Article
- Girdling behavior of the longhorn beetle modulates the host plant to enhance larval performance.BMC ecology and evolution · 2024Article
- A constitutive serine protease inhibitor suppresses herbivore performance in tea (Horticulture research · 2023Article
- Defense Strategies of Rice in Response to the Attack of the Herbivorous Insect,International journal of molecular sciences · 2023Review
- In order to lower the antinutritional activity of serine protease inhibitors, we need to understand their role in seed development.Frontiers in plant science · 2023Article
- TcTI, a Kunitz-type trypsin inhibitor from cocoa associated with defense against pathogens.Scientific reports · 2022Article
- Comparative transcriptome analysis of wheat in response to corn leaf aphid,Frontiers in plant science · 2022Article
- Characterization of a Bowman-Birk type trypsin inhibitor purified from seeds of Solanum surattense.Scientific reports · 2021Article
- TCMP-2 affects tomato flowering and interacts with BBX16, a homolog of the arabidopsis B-box MiP1b.Plant direct · 2020Article
- Article
- Comparative transcriptome and histological analyses of wheat in response to phytotoxic aphid Schizaphis graminum and non-phytotoxic aphid Sitobion avenae feeding.BMC plant biology · 2019Article
- Plant Serine Protease Inhibitors: Biotechnology Application in Agriculture and Molecular Farming.International journal of molecular sciences · 2019Review
- Oviposition byInternational journal of molecular sciences · 2018Article
- Transcriptomic Plasticity in the Arthropod GeneralistG3 (Bethesda, Md.) · 2018Article
- Review
- The alteration in the architecture of a T-DNA insertion rice mutant osmtd1 is caused by up-regulation of MicroRNA156f.Journal of integrative plant biology · 2015Article
- Mechanisms and ecological consequences of plant defence induction and suppression in herbivore communities.Annals of botany · 2015Review
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Solanaceaeous taxa produce diverse peptide serine proteinase inhibitors (SPIs), known antidigestive defenses that might also control endogenous plant proteases. If and how a plant coordinates and combines its different SPIs for the defense against herbivores and if these SPIs simultaneously serve developmental functions is unknown. We examine Solanum nigrum's SPI profile, comprising four different active inhibitors, of which the most abundant proved to be novel, to understand their functional specialization in an ecological context. Transcript and activity characterization revealed tissue-specific and insect-elicited accumulation patterns. Stable and transient gene silencing of all four SPIs revealed different specificities for target proteinases: the novel SPI2c displayed high specificity for trypsin and chymotrypsin, while two other SPI2 homologs were highly active against subtilisin. In field and lab experiments, we found all four SPIs to display herbivore- and gene-specific defensive properties, with dissimilar effects on closely related species. However, we did not observe any clear developmental phenotype in SPI-silenced plants, suggesting that SPIs do not play a major role in regulating endogenous proteases under the conditions studied. In summary, specific single SPIs or their combinations defend S. nigrum against generalist herbivores, while the defense against herbivores specialized on SPI-rich diets requires other unknown defense mechanisms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.