Evidence map›Paper›PMID 21176878›Full record

ReviewCurrent opinion in structural biology2011

Nucleosome structural studies.

Song Tan, Curt A Davey

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in structural biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 138 citations in OpenAlex.

  1. PARP1 Exhibits an Enzymatically Inactive Chromatin Binding Mode.bioRxiv : the preprint server for biology · 2026
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  9. The Role of Epigenetic Factors in the Pathogenesis of Psoriasis.International journal of molecular sciences · 2024
    Review
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  19. Biophysics of Chromatin Remodeling.Annual review of biophysics · 2021
    Review
  20. Review

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Song TanCenter for Eukaryotic Gene Regulation, Department of Biochemistry & Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA.
Curt A Davey
Nanyang Technological University · SGPennsylvania State University · US

Funding

Structural Basis for RCC1 Directed Recruitment of Ran GTPase to ChromatinR01GM088236 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI TAN, SONG · 2009 to 2017
$2.5M
STRUCTURE AND FUNCTION OF GENE REGULATORY COMPLEXESR01GM060489 · NIGMS · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI TAN, SONG · 2000 to 2010
$2.4M
NIGMS NIH HHS GM088236NIGMS NIH HHS R01 GM060489NIGMS NIH HHS R01 GM088236
6 · The paper itself

Abstract

Chromatin plays a fundamental role in eukaryotic genomic regulation, and the increasing awareness of the importance of epigenetic processes in human health and disease emphasizes the need for understanding the structure and function of the nucleosome. Recent advances in chromatin structural studies, including the first structures of nucleosomes containing the Widom 601 sequence and the structure of a chromatin protein-nucleosome assembly, have provided new insight into stretching of nucleosomal DNA, nucleosome positioning, binding of metal ions, drugs and therapeutic candidates to nucleosomes, and nucleosome recognition by nuclear proteins. These discoveries ensure promising future prospects for unravelling structural attributes of chromatin.

Indexed as

AnimalsDNAHumansNuclear ProteinsNucleosomesProtein BindingDNANuclear ProteinsNucleosomes

Identifiers

PMID21176878
PMCPMC3052702
OpenAlexW1969934670

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.