Evidence map›Paper›PMID 21176227›Full record

ReviewWorld journal of surgical oncology2010

Cell cyclins: triggering elements of cancer or not?

Michael Stamatakos, Victoria Palla, Ioannis Karaiskos, Konstantinos Xiromeritis, Ioannis Alexiou, Ioannis Pateras, Konstantinos Kontzoglou

Open access · goldAbstract readReview
In one paragraph

Review in World journal of surgical oncology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Upregulation of Cyclin B2 (American journal of cancer research · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Redox-Mediated Mechanism of Chemoresistance in Cancer Cells.Antioxidants (Basel, Switzerland) · 2019
    Review
  15. Article
  16. Article
  17. Article
  18. Over-expression of the long non-coding RNA HOTTIP inhibits glioma cell growth by BRE.Journal of experimental & clinical cancer research : CR · 2016
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Michael Stamatakos4th Department of Surgery, Medical School, University of Athens, Attikon General Hospital, Athens, Greece. mixalislak@gmail.com
Victoria Palla
Ioannis Karaiskos
Konstantinos Xiromeritis
Ioannis Alexiou
Ioannis Pateras
Konstantinos Kontzoglou
National and Kapodistrian University of Athens · GRUniversity General Hospital Attikon · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclins are indispensable elements of the cell cycle and derangement of their function can lead to cancer formation. Recent studies have also revealed more mechanisms through which cyclins can express their oncogenic potential. This review focuses on the aberrant expression of G1/S cyclins and especially cyclin D and cyclin E; the pathways through which they lead to tumour formation and their involvement in different types of cancer. These elements indicate the mechanisms that could act as targets for cancer therapy.

Indexed as

Cell CycleAnimalsCyclinsHumansNeoplasmsCyclins

Identifiers

PMID21176227
PMCPMC3016250
OpenAlexW2110249208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.