ArticleBMC plant biology2010
The FANTASTIC FOUR proteins influence shoot meristem size in Arabidopsis thaliana.
Article in BMC plant biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 81 citations in OpenAlex.
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- Dissection of genomic regions underlying early seedling vigour in chickpea through genome-wide association mapping.BMC plant biology · 2025Article
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- Distinct haplotypes and reversed dominance at a single-gene balanced polymorphism controlling heterodichogamy in two genera of wingnuts.Current biology : CB · 2025Article
- Genome-wide association mapping dissects the selective breeding of determinacy and photoperiod sensitivity in common bean (Phaseolus vulgaris L.).G3 (Bethesda, Md.) · 2025Article
- A special short-wing petal faba genome and genetic dissection of floral and yield-related traits accelerate breeding and improvement of faba bean.Genome biology · 2025Article
- Analysis and Functional Prediction of Core Bacteria in theMicroorganisms · 2024Article
- Developmental stages and episode-specific regulatory genes in andromonoecious melon flower development.Annals of botany · 2024Article
- GWAS supported by computer vision identifies large numbers of candidate regulators of in planta regeneration in Populus trichocarpa.G3 (Bethesda, Md.) · 2024Article
- CRISPR/Cas9-mediated mutations of FANTASTIC FOUR gene family for creating early flowering mutants in tomato.Plant biotechnology journal · 2024Article
- EARLY FLOWERING is a dominant gain-of-function allele of FANTASTIC FOUR 1/2c that promotes early flowering in tomato.Plant biotechnology journal · 2024Article
- Comparative RNA-Seq Analysis between Monoecious and Androecious Plants Reveals Regulatory Mechanisms Controlling Female Flowering inInternational journal of molecular sciences · 2023Article
- Oak stands along an elevation gradient have different molecular strategies for regulating bud phenology.BMC plant biology · 2023Article
- A genome wide association study to dissect the genetic architecture of agronomic traits in Andean lupin (Frontiers in plant science · 2022Article
- Expression analyses in Ginkgo biloba provide new insights into the evolution and development of the seed.Scientific reports · 2021Article
- A novel plant-fungal association reveals fundamental sRNA and gene expression reprogramming at the onset of symbiosis.BMC biology · 2021Article
- The rice VCS1 is identified as a molecular tool to mark and visualize the vegetative cell of pollen.Plant signaling & behavior · 2021Article
- Detection of Reproducible Major Effect QTL for Petal Traits in Garden Roses.Plants (Basel, Switzerland) · 2021Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThroughout their lives plants produce new organs from groups of pluripotent cells called meristems, located at the tips of the shoot and the root. The size of the shoot meristem is tightly controlled by a feedback loop, which involves the homeodomain transcription factor WUSCHEL (WUS) and the CLAVATA (CLV) proteins. This regulatory circuit is further fine-tuned by morphogenic signals such as hormones and sugars.
resultsHere we show that a family of four plant-specific proteins, encoded by the FANTASTIC FOUR (FAF) genes, has the potential to regulate shoot meristem size in Arabidopsis thaliana. FAF2 and FAF4 are expressed in the centre of the shoot meristem, overlapping with the site of WUS expression. Consistent with a regulatory interaction between the FAF gene family and WUS, our experiments indicate that the FAFs can repress WUS, which ultimately leads to an arrest of meristem activity in FAF overexpressing lines. The finding that meristematic expression of FAF2 and FAF4 is under negative control by CLV3 further supports the hypothesis that the FAFs are modulators of the genetic circuit that regulates the meristem.
conclusionThis study reports the initial characterization of the Arabidopsis thaliana FAF gene family. Our data indicate that the FAF genes form a plant specific gene family, the members of which have the potential to regulate the size of the shoot meristem by modulating the CLV3-WUS feedback loop.
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