ArticleInternational journal of colorectal disease2011
Qualitative and quantitative analysis of rectoanal inhibitory reflex (RAIR) modulation in functional bowel disorders.
Article in International journal of colorectal disease, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 7 citations in OpenAlex.
- Diagnostic testing for fecal incontinence.Clinics in colon and rectal surgery · 2014Review
- Morphological abnormalities of the recto-anal inhibitory reflex reflects symptom pattern in neurogenic bowel.Digestive diseases and sciences · 2012Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRectoanal inhibitory reflex (RAIR) is a physiological reflex implicated in anorectal continence. A lack of RAIR modulation is only described in spinal cord-injured patients with a lesion under L2. No quantitative data has been published concerning the normal modulation in amplitude and in duration in functional disorders.
methodsA retrospective analysis of anorectal manometry, performed in 40 safe-neurological patients, suffering from idiopathic constipation and/or faecal incontinence, has been done. RAIR were obtained by five successive rectal distensions (10-50 ml).Resting pressure, residual pressure, percentages of relaxation, slope and duration of inhibition were estimated. Four hypotheses of normal modulation in amplitude and duration were set up using these parameters. The cut-off values chosen for the hypotheses were similar to results obtained by calculating median value +/- 2SD of the parameters.
resultsAll the 40 patients had present RAIR. Concerning the modulation of RAIR, we tested the hypotheses with the aim of finding those applying to patient's largest number. Amplitude: 85% of the patients had a normal modulation defined by a difference >8 cm H2O between two non-consecutive residual pressure on three successive rectal distensions. DURATION: 77.5% of the patients had a normal modulation defined by a time difference >2 s between two non-consecutive durations on three successive rectal distensions.
conclusionDetermination of normal values of RAIR modulation in functional disorders is interesting in clinical practise, suggesting that the patients with a lack of normal RAIR modulation (in amplitude or in duration) may have a neurological disease.
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