Evidence map›Paper›PMID 21174102›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2011

Chemical priming for spinal cord injury: a review of the literature part II-potential therapeutics.

Martin M Mortazavi, Ketan Verma, Aman Deep, Fatemeh B Esfahani, Patrick R Pritchard, R Shane Tubbs, Nicholas Theodore

Abstract readReview
PubMed Publisher
In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. An update on spinal cord injury research.Neuroscience bulletin · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Martin M MortazaviDepartment of Neurosurgery, Barrow Neurological Institute, Phoenix, AR, USA.
Ketan Verma
Aman Deep
Fatemeh B Esfahani
Patrick R Pritchard
R Shane Tubbs
Nicholas Theodore

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSpinal cord injury is a complex cascade of reactions secondary to the initial mechanical trauma that puts into action the innate properties of the injured cells, the circulatory, inflammatory, and chemical status around them, into a non-permissive and destructive environment for neuronal function and regeneration. Priming means putting a cell, in a state of "arousal" towards better function. Priming can be mechanical as trauma is known to enhance activity in cells. MATERIALS AND

methodsA comprehensive review of the literature was performed to better understand the possible chemical primers used for spinal cord injuries.

conclusionsTaken together, many studies have shown various promising results using the substances outlined herein for treating SCI.

Indexed as

AnimalsHumansNerve Growth FactorsNerve RegenerationSpinal Cord InjuriesNerve Growth Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.