ArticleF1000 biology reports2010
Plk4/SAK/ZYG-1 in the regulation of centriole duplication.
Article in F1000 biology reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Disruption ofBone research · 2020Article
- Article
- A Short CEP135 Splice Isoform Controls Centriole Duplication.Current biology : CB · 2015Article
- Deuterosome-mediated centriole biogenesis.Developmental cell · 2013Article
- SmSak, the second Polo-like kinase of the helminth parasite Schistosoma mansoni: conserved and unexpected roles in meiosis.PloS one · 2012Article
- The importance of a single primary cilium.OrganogenesisReview
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Centrioles organize both centrosomes and cilia. Centriole duplication is tightly regulated and coordinated with the cell cycle to limit duplication to only once per cell cycle. Defects in centriole number and structure are commonly found in cancer. Plk4/SAK and the functionally related Caenorhabditis elegans ZYG-1 kinases initiate centriole duplication. Several recent studies have elucidated the regulated activity of these kinases and potential downstream targets for centriole assembly.
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Registered trials
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