ArticleMolecular cell2010
DNA replication: making two forks from one prereplication complex.
Article in Molecular cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Multiple pathways for licensing human replication origins.bioRxiv : the preprint server for biology · 2024Article
- Review
- Molecular mechanisms of eukaryotic origin initiation, replication fork progression, and chromatin maintenance.The Biochemical journal · 2020Article
- Analysis of cilia dysfunction phenotypes in zebrafish embryos depleted of Origin recognition complex factors.European journal of human genetics : EJHG · 2019Article
- Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- A journey through the microscopic ages of DNA replication.Protoplasma · 2017Review
- Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.Nature structural & molecular biology · 2017Article
- The Eukaryotic Replisome Goes Under the Microscope.Current biology : CB · 2016Review
- Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.Nature structural & molecular biology · 2016Article
- Replication stress: getting back on track.Nature structural & molecular biology · 2016Review
- DNA replication and homologous recombination factors: acting together to maintain genome stability.Chromosoma · 2013Review
- Mechanisms for initiating cellular DNA replication.Annual review of biochemistry · 2013Review
- Bringing single-molecule spectroscopy to macromolecular protein complexes.Trends in biochemical sciences · 2013Review
- Checkpoint kinase 2 (Chk2) inhibits the activity of the Cdc45/MCM2-7/GINS (CMG) replicative helicase complex.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Loading mechanisms of ring helicases at replication origins.Molecular microbiology · 2012Review
- Cdc6-induced conformational changes in ORC bound to origin DNA revealed by cryo-electron microscopy.Structure (London, England : 1993) · 2012Article
- The amino acid linker between the endonuclease and helicase domains of adeno-associated virus type 5 Rep plays a critical role in DNA-dependent oligomerization.Journal of virology · 2012Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The copying of chromosomal DNA initiates from a single nucleoprotein assembly called the prereplication complex. New findings in a recent issue of Molecular Cell (Yardimci et al., 2010) reveal that this complex dissolves into two independent replisomes that move away from each other as DNA synthesis ensues.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.