Evidence map›Paper›PMID 21172649›Full record

ArticleMolecular cell2010

Targeted ubiquitylation: the prey becomes predator.

Jun Yan, Yue Xiong

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Lipid transport between the endoplasmic reticulum and mitochondria.Cold Spring Harbor perspectives in biology · 2013
    Review
  2. Article
  3. Regulation and function of the TAZ transcription co-activator.International journal of biochemistry and molecular biology · 2011
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jun YanLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7295, USA.
Yue Xiong
University of North Carolina at Chapel Hill · US

Funding

The Physiological Function and Regulation of INK4 GenesR01CA068377 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MARZLUFF, WILLIAM F. · 1995 to 2021
$6.5M
The ROC-Cullin Family of E3 Ubiquitin LigasesR01GM067113 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI XIONG, YUE · 2003 to 2019
$5.4M
The Mammalian Cell Cycle Control and Tumor GenesisR01CA065572 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI XIONG, YUE · 1995 to 2009
$2.8M
NCI NIH HHS R01 CA065572NCI NIH HHS R01 CA068377NIGMS NIH HHS R01 GM067113
6 · The paper itself

Abstract

Being targeted for polyubiquitylation often means the end of life for the substrate protein. In this issue of Molecular Cell, Ouni et al. (2010) demonstrate that the yeast transcription factor Met4, a target of the SCF(Met30) E3 ligase for nonproteolytic polyubiquitylation, can also function to target its cofactors for proteolytic ubiquitylation by the same E3 ligase.

Identifiers

PMID21172649
PMCPMC3232680
OpenAlexW2027847697

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.