ArticleNeuron2010
The mechanism of rate remapping in the dentate gyrus.
Article in Neuron, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed.
- Dynamics of Dentate Gyrus Place Cells and Dentate Spikes during Spatial and Nonspatial Changes in Environments.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Inhibitory tone in the dentate gyrus dynamically prioritizes memory flexibility or stability by tuning a sensitivity-consistency continuum.PLoS biology · 2026Article
- Degeneracy Explains Diversity in Interneuronal Regulation of Pattern Separation in Heterogeneous Dentate Gyrus Networks.Function (Oxford, England) · 2025Article
- Firing patterns of ventral hippocampal neurons predict the exploration of anxiogenic locations.eLife · 2023Article
- Epistemic Autonomy: Self-supervised Learning in the Mammalian Hippocampus.Trends in cognitive sciences · 2021Review
- Article
- Ion-channel regulation of response decorrelation in a heterogeneous multi-scale model of the dentate gyrus.Current research in neurobiology · 2021Article
- Regulation of gamma-frequency oscillation by feedforward inhibition: A computational modeling study.Hippocampus · 2019Article
- Disrupted-in-schizophrenia 1 overexpression disrupts hippocampal coding and oscillatory synchronization.Hippocampus · 2019Article
- Coordinated representational reinstatement in the human hippocampus and lateral temporal cortex during episodic memory retrieval.Nature communications · 2019Article
- Disparate forms of heterogeneities and interactions among them drive channel decorrelation in the dentate gyrus: Degeneracy and dominance.Hippocampus · 2019Article
- How the Brain Represents Language and Answers Questions? Using an AI System to Understand the Underlying Neurobiological Mechanisms.Frontiers in computational neuroscience · 2019Article
- The cognitive nuances of surprising events: exposure to unexpected stimuli elicits firing variations in neurons of the dorsal CA1 hippocampus.Brain structure & function · 2018Article
- Coding of self-motion-induced and self-independent visual motion in the rat dorsomedial striatum.PLoS biology · 2018Article
- Article
- Place and Grid Cells in a Loop: Implications for Memory Function and Spatial Coding.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Overlap among Spatial Memories Triggers Repulsion of Hippocampal Representations.Current biology : CB · 2017Article
- Article
- Hippocampal Remapping and Its Entorhinal Origin.Frontiers in behavioral neuroscience · 2017Review
- A Spatial-Context Effect in Recognition Memory.Frontiers in behavioral neuroscience · 2017Article
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3 authors.
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Abstract
Rate remapping is a recently revealed neural code in which sensory information modulates the firing rate of hippocampal place cells. The mechanism underlying rate remapping is unknown. Its characteristic modulation, however, must arise from the interaction of the two major inputs to the hippocampus, the medial entorhinal cortex (MEC), in which grid cells represent the spatial position of the rat, and the lateral entorhinal cortex (LEC), in which cells represent the sensory properties of the environment. We have used computational methods to elucidate the mechanism by which this interaction produces rate remapping. We show that the convergence of LEC and MEC inputs, in conjunction with a competitive network process mediated by feedback inhibition, can account quantitatively for this phenomenon. The same principle accounts for why different place fields of the same cell vary independently as sensory information is altered. Our results show that rate remapping can be explained in terms of known mechanisms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.