ArticleNeuron2010
Multiple functions of the vesicular proton pump in nerve terminals.
Article in Neuron, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05711810 (Cardiac Transfer of SARS-CoV-2 Spike Protein Circulation Techniques - Medicine Induced Hemodialysis on "Vaccinated" Immune Attacks), which is not on this map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cardiac Transfer of SARS-CoV-2 Spike Protein Circulation Techniques - Medicine Induced Hemodialysis on "Vaccinated" Immune Attacks
Who cites it
8 citing papers in PubMed, 17 citations in OpenAlex.
- Proton Pump Inhibitors and Cognitive Health: Review on Unraveling the Dementia Connection and Co-morbid Risks.Current Alzheimer research · 2024Review
- Association between Migraines and Prior Proton Pump Inhibitor Use: A Nested Case-Control Study Using a National Health Screening Cohort.Pharmaceuticals (Basel, Switzerland) · 2022Article
- The Janus-like Association between Proton Pump Inhibitors and Dementia.Current Alzheimer research · 2021Article
- Proton Pump Inhibitors and Dementia: Physiopathological Mechanisms and Clinical Consequences.Neural plasticity · 2018Review
- Expression and role of V1A subunit of V-ATPases in gastric cancer cells.International journal of clinical oncology · 2015Article
- Proton pump inhibition increases rapid eye movement sleep in the rat.BioMed research international · 2014Article
- Emerging biogenesis technologies of extracellular vesicles for tissue regenerative therapeutics.Journal of tissue engineeringArticle
- Article
Corrections and comments
- Comment on
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synaptic vesicles are acidified by a proton pump (vATPase), which allows vesicular uptake of neurotransmitters. After vesicle exocytosis, continued operation of the vATPase would seem to serve no useful function. In this issue of Neuron, however, Zhang and colleagues show that continued pumping alkalinizes the cytoplasm, accelerating endocytosis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.