Evidence map›Paper›PMID 21172098›Full record

ArticleCanadian journal of psychiatry. Revue canadienne de psychiatrie2010

Time trends in mortality associated with depression: findings from the Stirling County study.

Jane M Murphy, Stephen E Gilman, Alain Lesage, Nicholas J Horton, Daniel Rasic, Nhi-Ha Trinh, Bibi Alamiri, Arthur M Sobol, Maurizio Fava, Jordan W Smoller

Open access · bronzeAbstract read
In one paragraph

Article in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 30 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Depression and mortality in a longitudinal study: 1952-2011.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017
    Article
  5. A Surveillance System to Monitor Excess Mortality of People With Mental Illness in Canada.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2015
    Article
  6. Random but Controlled Thoughts on Mental Health Epidemiology and Services Research.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2015
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Jane M MurphyDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, and Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts. murphy.jane@mgh.harvard.edu
Stephen E Gilman
Alain Lesage
Nicholas J Horton
Daniel Rasic
Nhi-Ha Trinh
Bibi Alamiri
Arthur M Sobol
Maurizio Fava
Jordan W Smoller
Massachusetts General Hospital · USHarvard University · USDalhousie University · CAHôpital Louis-H Lafontaine · CASmith College · US

Funding

LONGITUDINAL STUDY IN PSYCHIATRIC EPIDEMIOLOGYR01MH039576 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI MURPHY, JANE M · 1985 to 2007
$2.1M
NIMH NIH HHS R01 MH039576NIMH NIH HHS R01-MH39576-25
6 · The paper itself

Abstract

objectiveto address the question of whether a mortality risk associated with depression in a 1952 representative sample of Stirling County adults changed in a new sample in 1970, and whether there was a change in associations with cigarette smoking and alcoholism.

methodsample members were interviewed about depression and cigarette smoking. General physicians were interviewed by psychiatrists regarding alcoholism. Information about death as of December 31, 1992, was provided by Statistics Canada. Proportional hazards models were fitted in the 2 samples to assess the mortality risks associated with depression among men and women during 20 years of follow-up, and additionally among men with heavy smoking and alcoholism. Specific causes of death were investigated.

resultshazard ratios representing the association between depression and premature death among men were 2.6 (95% CI 1.4 to 4.9) and 2.8 (95% CI 1.5 to 5.1), respectively, in the 1952 and 1970 samples for the first 10 years of follow-up. Hazard ratios for women were 1.4 (95% CI 0.6 to 3.2) and 1.2 (95% CI 0.5 to 2.9). The risk associated with depression among men was independent of alcoholism and heavy smoking. Depression and alcoholism were significantly associated with death by external causes and circulatory disease; heavy smoking was significantly associated with malignant neoplasms.

conclusionthe mortality associated with depression did not change during the period from 1952 to 1970. Depressed men experienced a significant mortality risk that was not matched among depressed women and also was not due to alcoholism and heavy smoking.

Indexed as

AdultAge FactorsAlcoholismCanadaCause of DeathDepressive DisorderFemaleHumansMaleMiddle AgedMortalityProportional Hazards ModelsRisk FactorsSex FactorsSmoking

Identifiers

PMID21172098
PMCPMC3462356
OpenAlexW1493311425

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.