Evidence map›Paper›PMID 21169905›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2011

The ability of the skin to absorb heat; the effect of repeated exposure and age.

Jerrold Petrofsky, Neha Goraksh, Faris Alshammari, Mitali Mohanan, Janhavi Soni, Moxi Trivedi, Haneul Lee, Akshay N Hudlikar, Chia-hao Yang, Brindha Agilan and 5 more

Abstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. The effect of acute administration of vitamin D on micro vascular endothelial function in Caucasians and South Asian Indians.Medical science monitor : international medical journal of experimental and clinical research · 2013
    Trial
  2. CoQ10 and endothelial function in Asians from Korea compared to Asians born in the United States and US born Caucasians.Medical science monitor : international medical journal of experimental and clinical research · 2013
    Trial
  3. Differences in endothelial function between Korean-Asians and Caucasians.Medical science monitor : international medical journal of experimental and clinical research · 2012
    Trial
  4. Trial
  5. Anterior cruciate ligament elasticity and force for flexion during the menstrual cycle.Medical science monitor : international medical journal of experimental and clinical research · 2013
    Article
  6. What is more damaging to vascular endothelial function: Diabetes, age, high BMI, or all of the above?Medical science monitor : international medical journal of experimental and clinical research · 2013
    Article
  7. Review
  8. Article
  9. Review
  10. Reduced endothelial function in the skin in Southeast Asians compared to Caucasians.Medical science monitor : international medical journal of experimental and clinical research · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jerrold PetrofskyDepartment of Physical Therapy, Loma Linda University, Loma Linda, CA 92350, USA. jpetrofsky@llu.edu
Neha Goraksh
Faris Alshammari
Mitali Mohanan
Janhavi Soni
Moxi Trivedi
Haneul Lee
Akshay N Hudlikar
Chia-hao Yang
Brindha Agilan
Nikhila Pai
Tirupathi Chindam
Vengatesh Murugesan
Jong Eun Yim
Vahishta Katrak

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhen heat is applied to the skin, it is dissipated due to conductive heat flow in the tissue and the blood. While heat flow has been studied after applying a single heat exposure, the physiology of repeated exposures to local heat has not been well investigated. MATERIAL/

methodsTwenty male and female subjects in the age range of 20-65 years old participated in a series of experiments during which a thermode was placed on their leg above the quadriceps muscle for 20 minutes, and on 3 sequential days, to see the effect of repeated local heat on skin blood flow, skin temperature, and on caloric transfer from a thermode used to raise skin temperature.

resultsThe results of the experiment showed that, for young subjects, to raise skin temperature to 40 degrees C required more than double the calories required in older subjects. Further, in the younger subjects, the blood flow response in the first 20 minutes of heat exposure was over 30% higher than that seen in the older subjects. However, on the 2nd and 3rd day, the blood flow response of the younger subjects, was not significantly different between day 2 and 3, but was significantly less than day 1. There was no statistical difference in the blood flow response between day 1, 2 and 3 in the older subjects. In the younger subjects, in the 2 and 3rd day, the number of calories needed to warm the skin was also significantly less than that seen in the first day.

conclusionsIn younger subjects but not older subjects, there appears to be some degree of acclimatization with an enhanced blood flow response in the first day that was protective to the skin which was not seen in repeated heat exposure.

Indexed as

Hot TemperatureSkin Physiological PhenomenaAcclimatizationAdultAge FactorsAnalysis of VarianceFemaleHumansMaleMiddle AgedRegional Blood FlowSkin

Identifiers

PMID21169905
PMCPMC3524686

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.