Evidence map›Paper›PMID 21169686›Full record

ArticleJournal of synchrotron radiation2011

Structure analysis of group I plant nucleases.

Jan Dohnálek, Tomáš Koval', Petra Lipovová, Tomáš Podzimek, Jaroslav Matoušek

Open access · hybridAbstract read
In one paragraph

Article in Journal of synchrotron radiation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Jan DohnálekInstitute of Macromolecular Chemistry AS CR, v.v.i., Heyrovského nám. 2, 162 06 Praha 6, Czech Republic. dohnalek007@gmail.com
Tomáš Koval'
Petra Lipovová
Tomáš Podzimek
Jaroslav Matoušek
University of Chemistry and Technology, Prague · CZCzech Academy of Sciences, Biology Centre · CZCzech Academy of Sciences, Institute of Physics · CZInstitute of Macromolecular Chemistry · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anticancer drugs attacking nucleic acids of the target cells have so far been based on animal or fungal ribonucleases. Plant nucleases have been proved to exhibit decreased cytotoxic side effects. Tomato bifunctional nuclease 1 with activity against both single-stranded and double-stranded RNA and DNA was produced in tobacco leaves as recombinant protein. The enzyme crystallizes under several different crystallization conditions. The presence of Zn(2+) ions was confirmed by X-ray fluorescence. First crystallographic data were obtained.

Indexed as

DNA, Single-StrandedEndodeoxyribonucleasesEndoribonucleasesNicotianaRecombinant ProteinsRNA, Double-StrandedSolanum lycopersicumX-Ray DiffractionZincDNA, Single-StrandedEndodeoxyribonucleasesEndoribonucleasesRecombinant ProteinsRNA, Double-StrandedZinc

Identifiers

PMID21169686
PMCPMC3004249
OpenAlexW2168033728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.