ArticleNucleic acids research2011
Insights into the evolution of Archaea and eukaryotic protein modifier systems revealed by the genome of a novel archaeal group.
Article in Nucleic acids research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers.
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162 citing papers in PubMed.
- Asgard archaea: have we found our microbial ancestors?The EMBO journal · 2026Review
- Branched-chain amino acid specialization drove diversification within Calditenuaceae (Caldarchaeia) and enables their cultivation.Nature communications · 2026Article
- Ecological distribution and environmental preference of the deep-branching archaeal lineage in high-temperature hot springs of Central Kyushu, Japan.Extremophiles : life under extreme conditions · 2025Article
- Groundwater Microbial Diversity Associated With Icelandic Basaltic Subsurface Environments.Environmental microbiology reports · 2025Article
- Article
- Investigation of the global translational response to oxidative stress in the model archaeonmSphere · 2025Article
- Unveiling the life of archaea in sediments: Diversity, metabolic potentials, and ecological roles.iMetaOmics · 2025Review
- Microbial diversity of hot springs of the Kuril Islands.BMC microbiology · 2024Article
- Microbial diversity and biogeochemical interactions in the seismically active and COEnvironmental microbiome · 2024Article
- The dynamic history of prokaryotic phyla: discovery, diversity and division.International journal of systematic and evolutionary microbiology · 2024Review
- Interactome ofInternational journal of molecular sciences · 2023Article
- Metabolic versatility ofFrontiers in microbiology · 2023Article
- Probing archaeal cell biology: exploring the use of dyes in the imaging ofFrontiers in microbiology · 2023Article
- Evolutionary diversification of the autophagy-related ubiquitin-like conjugation systems.Autophagy · 2022Article
- The expanding Asgard archaea invoke novel insights into Tree of Life and eukaryogenesis.mLife · 2022Article
- An essential role for tungsten in the ecology and evolution of a previously uncultivated lineage of anaerobic, thermophilic Archaea.Nature communications · 2022Article
- Asgard archaea shed light on the evolutionary origins of the eukaryotic ubiquitin-ESCRT machinery.Nature communications · 2022Article
- Microbial diversity in extreme environments.Nature reviews. Microbiology · 2022Review
- Insight into the symbiotic lifestyle of DPANN archaea revealed by cultivation and genome analyses.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Insights into ecological roles of uncultivated bacteria in Katase hot spring sediment from long-read metagenomics.Frontiers in microbiology · 2022Article
102 more citing papers are in PubMed but not listed here.
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12 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The domain Archaea has historically been divided into two phyla, the Crenarchaeota and Euryarchaeota. Although regarded as members of the Crenarchaeota based on small subunit rRNA phylogeny, environmental genomics and efforts for cultivation have recently revealed two novel phyla/divisions in the Archaea; the 'Thaumarchaeota' and 'Korarchaeota'. Here, we show the genome sequence of Candidatus 'Caldiarchaeum subterraneum' that represents an uncultivated crenarchaeotic group. A composite genome was reconstructed from a metagenomic library previously prepared from a microbial mat at a geothermal water stream of a sub-surface gold mine. The genome was found to be clearly distinct from those of the known phyla/divisions, Crenarchaeota (hyperthermophiles), Euryarchaeota, Thaumarchaeota and Korarchaeota. The unique traits suggest that this crenarchaeotic group can be considered as a novel archaeal phylum/division. Moreover, C. subterraneum harbors an ubiquitin-like protein modifier system consisting of Ub, E1, E2 and small Zn RING finger family protein with structural motifs specific to eukaryotic system proteins, a system clearly distinct from the prokaryote-type system recently identified in Haloferax and Mycobacterium. The presence of such a eukaryote-type system is unprecedented in prokaryotes, and indicates that a prototype of the eukaryotic protein modifier system is present in the Archaea.
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