ArticleThe Journal of pediatrics2011
Functional brown adipose tissue is related to muscle volume in children and adolescents.
Article in The Journal of pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Study on the Association Between Brown Adipose Tissue Activation and White Adipose Tissue Accumulation in Successfully Treated Pediatric Malignancy
Study of the Effect of Capsinoid Supplementation on Brown Adipose Tissue in Obese Adolescents
Who cites it
38 citing papers in PubMed, 73 citations in OpenAlex.
- Prevention of activated brown adipose tissue onScientific reports · 2023Trial
- Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets.MedComm · 2026Review
- Article
- Article
- Brown to White Fat Transition Overlap With Skeletal Muscle During Development of Larger Mammals: Is it a Coincidence?Journal of the Endocrine Society · 2022Review
- Association of Type 2 Deiodinase Thr92Ala Polymorphism with Pediatric Obesity in Japanese Children: A Case-Control Study.Children (Basel, Switzerland) · 2022Article
- Impact of brown adipose tissue vascular density on body adiposity in healthy Japanese infants and children.Obesity science & practice · 2022Article
- Brown adipose tissue fat-fraction is associated with skeletal muscle adiposity.European journal of applied physiology · 2022Article
- Brown Adipose Tissue: New Challenges for Prevention of Childhood Obesity. A Narrative Review.Nutrients · 2021Review
- Effect of Propranolol on 18F-Fluorodeoxyglucose Uptake in Brown Adipose Tissue in Children and Young Adults with Neoplastic Diseases.Molecular imaging and biology · 2021Article
- Developmental and functional heterogeneity of thermogenic adipose tissue.Journal of molecular cell biology · 2020Review
- Neuroendocrine drivers of risk and resilience: The influence of metabolism & mitochondria.Frontiers in neuroendocrinology · 2019Review
- Brown adipose tissue in prepubertal children: associations with sex, birthweight, and metabolic profile.International journal of obesity (2005) · 2019Article
- Brown and Beige Adipose Tissue and Aging.Frontiers in endocrinology · 2019Review
- Association between supraclavicular brown adipose tissue composition at birth and adiposity gain from birth to 6 months of age.Pediatric research · 2017Article
- Automatic Segmentation and Quantification of White and Brown Adipose Tissues from PET/CT Scans.IEEE transactions on medical imaging · 2017Article
- Brown adipose tissue and bone.International journal of obesity supplements · 2015Review
- Differential lncRNA expression profiles in brown and white adipose tissues.Molecular genetics and genomics : MGG · 2015Article
- Article
- Fat and Bone: An Odd Couple.Frontiers in endocrinology · 2015Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveWe examined whether the depiction of brown adipose tissue (BAT) with positron emission tomography/computed tomography (PET/CT) in pediatric patients is associated with anthropometric measures. STUDY
designWe determined measures of body mass, adiposity, and musculature in 71 children and adolescents who underwent PET/CT examinations and compared patients with and without BAT. We used regression analyses to assess the relation between BAT and anthropometric measures.
resultsA total of 30 patients (42%) had BAT depicted on PET/CT, 10 of 26 girls (38%) and 20 of 45 boys (44%). Compared with patients without functional BAT, patients with BAT had significantly greater neck musculature (1880 ± 908 cm(3) versus 1299 ± 806 cm(3); P = .028 for boys and 1295 ± 586 cm(3) versus 854 ± 392 cm(3); P = .030 for girls) and gluteus musculature (1359 ± 373 cm(3) versus 1061 ± 500 cm(3); P = .032 for boys and 1138 ± 425 cm(3) versus 827 ± 297 cm(3); P = .038 for girls), but no differences in age, body mass index, or measures of subcutaneous fat. With logistic regression analyses, neck and pelvic musculature predicted the presence of BAT independently of age, sex, body size, and season of scan (P = .018 and .009, respectively).
conclusionPediatric patients with visualized BAT on PET/CT examinations had significantly greater muscle volume than patients with no visualized BAT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.