ArticleChemistry & biology2010
Epigenetics gets sweeter: O-GlcNAc joins the "histone code".
Article in Chemistry & biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The human O-GlcNAcome database and meta-analysis.Scientific data · 2021Pooled it
- PerturbingCells · 2026Article
- The gut-heart dialogue: an epigenetic perspective on myocardial infarction.NPJ biofilms and microbiomes · 2026Review
- Nutrient inputs and social metabolic control of T cell fate.Cell metabolism · 2024Review
- An Epigenetic Role of Mitochondria in Cancer.Cells · 2022Review
- Review
- Genetically Encoded Green Fluorescent Biosensors for Monitoring UDP-GlcNAc in Live Cells.ACS central science · 2021Article
- The neuroscience of sugars in taste, gut-reward, feeding circuits, and obesity.Cellular and molecular life sciences : CMLS · 2020Review
- Post-translational modifications as key regulators of apicomplexan biology: insights from proteome-wide studies.Molecular microbiology · 2018Review
- Profiling of Protein O-GlcNAcylation in Murine CD8ACS chemical biology · 2017Article
- O-GlcNAcylation of SKN-1 modulates the lifespan and oxidative stress resistance in Caenorhabditis elegans.Scientific reports · 2017Article
- Identification of the nuclear localisation signal of O-GlcNAc transferase and its nuclear import regulation.Scientific reports · 2016Article
- Histone Modifications and Cancer.Cold Spring Harbor perspectives in biology · 2016Review
- Computer-aided Molecular Design of Compounds Targeting Histone Modifying Enzymes.Computational and structural biotechnology journal · 2015Review
- Epigenetic regulation of female puberty.Frontiers in neuroendocrinology · 2015Review
- Undetectable histone O-GlcNAcylation in mammalian cells.Epigenetics · 2015Article
- O-GlcNAc and the epigenetic regulation of gene expression.The Journal of biological chemistry · 2014Review
- Article
- Immediate effects of a single exercise bout on protein O-GlcNAcylation and chromatin regulation of cardiac hypertrophy.American journal of physiology. Heart and circulatory physiology · 2013Article
- Epigenetic switching by the metabolism-sensing factors in the generation of orexin neurons from mouse embryonic stem cells.The Journal of biological chemistry · 2013Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
O-GlcNAcylation has now been added to the growing list of histone modifications making up the multifaceted "histone-code" (Sakabe et al., 2010). The sites of O-GlcNAc-histone modification hint at a role in chromatin remodeling, thus adding to mounting evidence that O-GlcNAc cycling sits atop a robust regulatory network maintaining higher-order chromatin structure and epigenetic memory.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.