Evidence map›Paper›PMID 21167860›Full record

ArticleVaccine2011

The potential economic value of a hookworm vaccine.

Bruce Y Lee, Kristina M Bacon, Rachel Bailey, Ann E Wiringa, Kenneth J Smith

Abstract read
In one paragraph

Article in Vaccine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Impact and cost-effectiveness of new tuberculosis vaccines in low- and middle-income countries.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  10. Review
  11. Review
  12. Article
  13. Overcoming the global burden of neglected tropical diseases.Therapeutic advances in infectious disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bruce Y LeePublic Health Computational and Operations Research, PA, USA. BYL1@pitt.edu
Kristina M Bacon
Rachel Bailey
Ann E Wiringa
Kenneth J Smith

Funding

Training, Outreach & Diversity ComponentU54GM088491 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LAKOSKI, JOAN M · 2009 to 2018
$16.7M
NIGMS NIH HHS 1U54GM088491-0109NIGMS NIH HHS U54 GM088491
6 · The paper itself

Abstract

Hookworm infection is a significant problem worldwide. As development of hookworm vaccine proceeds, it is essential for vaccine developers and manufacturers, policy makers, and other public health officials to understand the potential costs and benefits of such a vaccine. We developed a decision analytic model to evaluate the cost-effectiveness of introducing a hookworm vaccine into two populations in Brazil: school-age children and non-pregnant women of reproductive age. Results suggest that a vaccine would provide not only cost savings, but potential health benefits to both populations. In fact, the most cost-effective intervention strategy may be to combine vaccine with current drug treatment strategies.

Indexed as

AdolescentAdultAncylostomatoideaAnimalsBrazilChildCost-Benefit AnalysisFemaleHookworm InfectionsHumansVaccinesVaccines

Identifiers

PMID21167860
PMCPMC3038553

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.