Evidence map›Paper›PMID 21167200›Full record

ArticleJournal of neuroscience methods2011

Precision rodent whisker stimulator with integrated servo-locked control and displacement measurement.

Jennifer L Walker, Fernanda Monjaraz-Fuentes, Christi R Pedrow, David M Rector

Open access · greenAbstract read
In one paragraph

Article in Journal of neuroscience methods, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jennifer L WalkerDepartment of Veterinary Comparative Anatomy and Pharmacology, Washington State University, 205 Wegner Hall, Pullman, WA 99163, USA.
Fernanda Monjaraz-Fuentes
Christi R Pedrow
David M Rector
Washington State University · US

Funding

ADVANCED OPTICAL IMAGE PROBE FOR NEUROPHYSIOLOGYR01MH060263 · NIMH · WASHINGTON STATE UNIVERSITY · PI RECTOR, DAVID M · 2001 to 2009
$2.8M
Implantable 16-256 channel data system for sleep in miceR01MH071830 · NIMH · WASHINGTON STATE UNIVERSITY · PI RECTOR, DAVID M · 2006 to 2010
$1.6M
NIMH NIH HHS MH60263NIMH NIH HHS MH71830NIMH NIH HHS R01 MH060263NIMH NIH HHS R01 MH071830
6 · The paper itself

Abstract

We developed a high speed voice coil based whisker stimulator that delivers precise deflections of a single whisker or group of whiskers in a repeatable manner. The device is miniature, quiet, and inexpensive to build. Multiple stimulators fit together for independent stimulation of four or more whiskers. The system can be used with animals under anesthesia as well as awake animals with head-restraint, and does not require trimming the whiskers. The system can deliver 1-2 mm deflections in 2 ms resulting in velocities up to 900 mm/s to attain a wide range of evoked responses. Since auditory artifacts can influence behavioral studies using whisker stimulation, we tested potential effects of auditory noise by recording somatosensory evoked potentials (SEP) with varying auditory click levels, and with/without 80 dBa background white noise. We found that auditory clicks as low as 40 dBa significantly influence the SEP. With background white noise, auditory clicks as low as 50 dBa were still detected in components of the SEP. For behavioral studies where animals must learn to respond to whisker stimulation, these sounds must be minimized. Together, the stimulator and data system can be used for psychometric vigilance tasks, mapping of the barrel cortex and other electrophysiological paradigms.

Indexed as

Acoustic StimulationAfferent PathwaysAnimalsEvoked Potentials, SomatosensoryFemalePhysical StimulationRatsRats, Sprague-DawleyReaction TimeSomatosensory CortexVibrissae

Identifiers

PMID21167200
PMCPMC3042047
OpenAlexW2042481593

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.