ArticleBMC genomics2010
Temporal transcriptomic response during arsenic stress in Herminiimonas arsenicoxydans.
Article in BMC genomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 70 citations in OpenAlex.
- As(III) Exposure Induces a Zinc Scarcity Response and Restricts Iron Uptake in High-Level Arsenic-Resistant Paenibacillus taichungensis Strain NC1.Applied and environmental microbiology · 2022Article
- Looking for the mechanism of arsenate respiration ofFrontiers in microbiology · 2022Article
- Discerning the role of a functional arsenic-resistance cassette in the evolution and adaptation of a rice pathogen.Microbial genomics · 2021Article
- Analysis of temporal gene regulation of Listeria monocytogenes revealed distinct regulatory response modes after exposure to high pressure processing.BMC genomics · 2021Article
- Arsenate-Induced Changes in Bacterial Metabolite and Lipid Pools during Phosphate Stress.Applied and environmental microbiology · 2021Article
- Introducing the ArsR-Regulated Arsenic Stimulon.Frontiers in microbiology · 2021Article
- Cellular response of Brevibacterium casei #NIOSBA88 to arsenic and chromium-a proteomic approach.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Article
- Metabolic Responses to Arsenite Exposure Regulated through Histidine Kinases PhoR and AioS inMicroorganisms · 2020Article
- Microbial Oxidation of Arsenite: Regulation, Chemotaxis, Phosphate Metabolism and Energy Generation.Frontiers in microbiology · 2020Review
- Genomic Variation and Arsenic Tolerance Emerged as Niche Specific Adaptations by DifferentFrontiers in microbiology · 2020Article
- Arsenic Response of Three AltiplanicFrontiers in microbiology · 2019Article
- Transcriptomic Analysis of TwoFrontiers in microbiology · 2019Article
- Differential protein expression in a marine-derived3 Biotech · 2018Article
- Expression of the arsenite oxidation regulatory operon in Rhizobium sp. str. NT-26 is under the control of two promoters that respond to different environmental cues.MicrobiologyOpen · 2018Article
- A Genomic Outlook on Bioremediation: The Case of Arsenic Removal.Frontiers in microbiology · 2018Review
- Comparison of biofilm formation and motility processes in arsenic-resistant Thiomonas spp. strains revealed divergent response to arsenite.Microbial biotechnology · 2017Article
- Arsenite oxidation regulator AioR regulates bacterial chemotaxis towards arsenite in Agrobacterium tumefaciens GW4.Scientific reports · 2017Article
- Comparative Genomics Analysis of a NewFrontiers in microbiology · 2017Article
- Article
- Microbial Antimony Biogeochemistry: Enzymes, Regulation, and Related Metabolic Pathways.Applied and environmental microbiology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundArsenic is present in numerous ecosystems and microorganisms have developed various mechanisms to live in such hostile environments. Herminiimonas arsenicoxydans, a bacterium isolated from arsenic contaminated sludge, has acquired remarkable capabilities to cope with arsenic. In particular our previous studies have suggested the existence of a temporal induction of arsenite oxidase, a key enzyme in arsenic metabolism, in the presence of As(III).
resultsMicroarrays were designed to compare gene transcription profiles under a temporal As(III) exposure. Transcriptome kinetic analysis demonstrated the existence of two phases in arsenic response. The expression of approximatively 14% of the whole genome was significantly affected by an As(III) early stress and 4% by an As(III) late exposure. The early response was characterized by arsenic resistance, oxidative stress, chaperone synthesis and sulfur metabolism. The late response was characterized by arsenic metabolism and associated mechanisms such as phosphate transport and motility. The major metabolic changes were confirmed by chemical, transcriptional, physiological and biochemical experiments. These early and late responses were defined as general stress response and specific response to As(III), respectively.
conclusionGene expression patterns suggest that the exposure to As(III) induces an acute response to rapidly minimize the immediate effects of As(III). Upon a longer arsenic exposure, a broad metabolic response was induced. These data allowed to propose for the first time a kinetic model of the As(III) response in bacteria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.