ArticleActa paediatrica (Oslo, Norway : 1992)2011
Placental programming of blood pressure in Indian children.
Article in Acta paediatrica (Oslo, Norway : 1992), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed.
- Applying AI models to digital placental photographs to automate and improve morphology assessments.medRxiv : the preprint server for health sciences · 2026Article
- Maternal Diabetes and Cardiovascular Health in the Offspring.Pediatric cardiology · 2025Article
- Hypertension and Reproduction.Current hypertension reports · 2020Review
- Placental transporter localization and expression in the Human: the importance of species, sex, and gestational age differences†.Biology of reproduction · 2017Review
- Blood pressure and anthropometry in children treated with stimulants: a longitudinal cohort study with an individual approach.Neuropsychiatric disease and treatment · 2017Article
- Cohort profile: Mysore parthenon birth cohort.International journal of epidemiology · 2015Observational
- Placental contribution to the origins of sexual dimorphism in health and diseases: sex chromosomes and epigenetics.Biology of sex differences · 2013Article
- Analysis of genetic interactions involving maternal and offspring genotypes at different Loci: power simulation and application to testicular cancer.Genetic epidemiology · 2012Article
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- Childhood cardiovascular risk factors in South Asians: A cause of concern for adult cardiovascular disease epidemic.Annals of pediatric cardiology · 2011Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
aimTo determine whether the size and shape of the placental surface predict blood pressure in childhood.
methodsWe studied blood pressure in 471 nine-year-old Indian children whose placental length, breadth and weight were measured in a prospective birth cohort study.
resultsIn the daughters of short mothers (<median height), systolic blood pressure (SBP) rose as placental breadth increased (β = 0.69 mmHg/cm, p = 0.05) and as the ratio of placental surface area to birthweight increased (p = 0.0003). In the daughters of tall mothers, SBP rose as the difference between placental length and breadth increased (β = 1.40 mmHg/cm, p = 0.007), that is as the surface became more oval. Among boys, associations with placental size were only statistically significant after adjusting for current BMI and height. After adjustment, SBP rose as placental breadth, area and weight decreased (for breadth β = -0.68 mmHg/cm, p < 0.05 for all three measurements).
conclusionsThe size and shape of the placental surface predict childhood blood pressure. Blood pressure may be programmed by variation in the normal processes of placentation: these include implantation, expansion of the chorionic surface in mid-gestation and compensatory expansion of the chorionic surface in late gestation.
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