ReviewEuropean journal of pediatrics2011
Eponym: Papillon-Lefevre syndrome.
Review in European journal of pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 45 citations in OpenAlex.
- Dipeptidyl Peptidase 1 Inhibitor AZD7986 Induces a Sustained, Exposure-Dependent Reduction in Neutrophil Elastase Activity in Healthy Subjects.Clinical pharmacology and therapeutics · 2018Trial
- Identification of a novel compound heterozygous mutation and a homozygous mutation of SLURP1 in Chinese families with Mal de Meleda.BMC medical genomics · 2023Article
- Diagnosis of Papillon-Lefèvre syndrome: review of the literature and a case report.Postepy dermatologii i alergologii · 2020Review
- A Mutation in Cathepsin C Gene Causing Papillon-Lefèvre Syndrome in a Saudi Patient: A Case Report.Cureus · 2020Article
- Primary immunodeficiencies reveal the essential role of tissue neutrophils in periodontitis.Immunological reviews · 2019Review
- Papillon-Lefèvre Syndrome: Diagnosis, Dental Management, and a Case Report.Case reports in dentistry · 2019Article
- Periodontal and other oral manifestations of immunodeficiency diseases.Oral diseases · 2017Review
- Papillon-Lefèvre syndrome: a series of five cases among siblings.Journal of medical case reports · 2016Article
- Papillion-Lefèvre Syndrome: Periodontists' Perspective.Case reports in dentistry · 2015Article
- Papillon-Lefèvre syndrome patient reveals species-dependent requirements for neutrophil defenses.The Journal of clinical investigation · 2014Article
- Palmoplantar keratoderma with dental abnormalities.Indian dermatology online journal · 2014Article
- Multiple cerebral abscesses in Papillon-Lefèvre syndrome.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2013Article
- Approach to a Child with Primary Immunodeficiency Made Simple.Indian dermatology online journalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Papillon-Lefevre Syndrome (PLS) is a very rare autosomal recessive disorder characterized by palmoplantar hyperkeratosis and severe early onset periodontitis, affecting the primary and permanent dentition. The syndrome was first described by Papillon and Lefevre in 1924. Genetic, immunologic, and microbiologic factors are suggested as responsible for the initiation and progression of the disease. A point mutation of cathepsin C gene has recently been detected in PLS. A multidisciplinary approach is important for management .The prognosis has improved with the early recognition of the syndrome, effective professional supervision, and home care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.