ArticleIndian journal of pediatrics2011
Neonatal sepsis in a tertiary care hospital in South India: bacteriological profile and antibiotic sensitivity pattern.
Article in Indian journal of pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.
- Burden of bacterial resistance among neonatal infections in low income countries: how convincing is the epidemiological evidence?BMC infectious diseases · 2015Pooled it
- Cerebral blood flow velocity in early-onset neonatal sepsis and its clinical significance.European journal of pediatrics · 2012Trial
- Prognostic Role of NLR and MPV/PLT Ratio in Pediatric Sepsis - Hope or Hype?Indian journal of pediatrics · 2026Article
- Antibiotic Prescription Practice and Resistance Patterns of Bacterial Isolates from a Neonatal Intensive Care Unit: A Retrospective Study from Jordan.Antibiotics (Basel, Switzerland) · 2025Article
- Observational
- Impact of Kangaroo Mother Care on Skin Microbiome of Very Preterm Infants - A Pilot Study.Indian journal of pediatrics · 2024Article
- Bacteriological profiles and antibiotic susceptibility of neonatal sepsis in a university hospital of Northern India.Journal of family medicine and primary care · 2023Article
- Relationship between antibiotic consumption pattern and antibiotic resistance in neonatal sepsis.Medicine and pharmacy reports · 2023Article
- Antibiotic Resistance Patterns of Bacterial Isolates from Neonatal Sepsis Patients at University Hospital of Leipzig, Germany.Antibiotics (Basel, Switzerland) · 2021Article
- Prevalence of Extended-SpectrumInternational journal of microbiology · 2021Review
- Clinical Symptoms, Pathogen Spectrum, Risk Factors and Antibiogram of Suspected Neonatal Sepsis Cases in Tertiary Care Hospital of Southern Part of Nepal: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2020Article
- Article
- Blood culture result profile and antimicrobial resistance pattern: a report from neonatal intensive care unit (NICU), Asella teaching and referral hospital, Asella, south East Ethiopia.Antimicrobial resistance and infection control · 2019Observational
- Changing Trend of Neonatal Septicemia and Antibiotic Susceptibility Pattern of Isolates in Nepal.International journal of pediatrics · 2019Article
- Bacteriological profile of neonatal sepsis and antibiotic susceptibility pattern of isolates admitted at Kanti Children's Hospital, Kathmandu, Nepal.BMC research notes · 2018Article
- Bacterial etiologic agents causing neonatal sepsis and associated risk factors in Gondar, Northwest Ethiopia.BMC pediatrics · 2017Article
- Penicillin-Resistant trend of Streptococcus pneumoniae in Asia: A systematic review.Iranian journal of microbiology · 2014Review
- Blood culture isolates in neonatal sepsis and their sensitivity in Anand District of India.Indian journal of pediatrics · 2014Article
- Isolation of MRSA, ESBL and AmpC - β -lactamases from Neonatal Sepsis at a Tertiary Care Hospital.Journal of clinical and diagnostic research : JCDR · 2014Article
- Bacteriological profile of neonatal septicemia and antibiotic susceptibility pattern of the isolates.Journal of natural science, biology, and medicine · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify the common bacterial pathogens associated with neonatal sepsis and their antibiotic susceptibility pattern.
methodsThis prospective observational cohort study was done in a tertiary care teaching hospital located in South India for a period of 2 years. All the admitted inborn and out born neonates during this study period were screened for sepsis based on the clinical features and septic screening. All infants satisfying the criteria for sepsis were subjected to blood culture. Growths, if any, were noted and standard antibiotic sensitivity testing was done by Kirby-Bauer disk diffusion method. The Chi-square test or Fisher's exact test was used to compare two groups.
resultsOut of the 120 clinically suspected and positive screening test cases of neonatal sepsis, 41.6% (50 of 120) were culture-proven cases of neonatal sepsis. Klebsiella pneumoniae was isolated from 66% of culture positive cases followed by Coagulase-negative staphylococci in 12% of cases. Klebsiella pneumoniae was resistant to most of the antibiotics tested except amikacin and meropenem. Of the total 33 Klebsiella pneumoniae isolates, 16 (32.0%) were ESBL producers. The prevalence of ESBL producing Klebsiella pneumoniae during two month outbreak and rest of the study period was 83.3% (15 of 18) and 20% (3 of 15) respectively (P value 0.0010).
conclusionsKlebsiella pneumoniae was the most common agent causing both early-onset and late-onset sepsis and significantly associated with sepsis in inborn babies. Amikacin should be used along with the third-generation cephalosporins for empirical treatment of gram-negative neonatal sepsis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.