ArticleKorean journal of urology2010
Effect of korean red ginseng on testicular tissue injury after torsion and detorsion.
Article in Korean journal of urology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 38 citations in OpenAlex.
- Antioxidant Strategies in Testicular Ischemia-Reperfusion Injury-Translational Insights and Clinical Implications for Testicular Torsion Management.Antioxidants (Basel, Switzerland) · 2026Review
- Panax ginseng nanoemulsion for counteracting male infertility via modulating sex hormones and oxidative stress in a rat model.Scientific reports · 2024Article
- The role of red ginseng in men's reproductive health: a literature review.Basic and clinical andrology · 2023Review
- Ginseng® as a reproductive enhancer agent for African catfish, Clarias gariepinus (Burchell, 1822).Fish physiology and biochemistry · 2022Article
- Attenuation Effect of Salvianolic Acid B on Testicular Ischemia-Reperfusion Injury in Rats.Oxidative medicine and cellular longevity · 2022Article
- Korean Red Ginseng aqueous extract improves markers of mucociliary clearance by stimulating chloride secretion.Journal of ginseng research · 2021Article
- Testicular Torsion and Spermatogenesis.Advances in experimental medicine and biology · 2021Article
- Tradition to Pathogenesis: A Novel Hypothesis for Elucidating the Pathogenesis of Diseases Based on the Traditional Use of Medicinal Plants.Frontiers in pharmacology · 2021Review
- Combination of Korean Red Ginseng Extract and Hydrogen-Rich Water Improves Spermatogenesis and Sperm Motility in Male Mice.Chinese journal of integrative medicine · 2020Article
- Effects of ingredients of Korean brown rice cookies on attenuation of cholesterol level and oxidative stress in high-fat diet-fed mice.Nutrition research and practice · 2017Article
- Antioxidants in experimental ischemia-reperfusion injury of the testis: Where are we heading towards?World journal of methodology · 2017Review
- Efficacy of Compound Therapy by Ginseng and Ciprofloxacin on Bacterial Prostatitis.Cell journal · 2016Article
- The Effect of Korean Red Ginseng on Sexual Function in Premenopausal Women: Placebo-Controlled, Double-Blind, Crossover Clinical Trial.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Mechanisms of testicular torsion and potential protective agents.Nature reviews. Urology · 2014Review
- A new validated analytical method for the quality control of red ginseng products.Journal of ginseng research · 2013Article
- Red ginseng abrogates oxidative stress via mitochondria protection mediated by LKB1-AMPK pathway.BMC complementary and alternative medicine · 2013Article
- Red ginseng supplementation more effectively alleviates psychological than physical fatigue.Journal of ginseng research · 2011Article
- Comparison of intraperitoneal and intratesticular ozone therapy for the treatment of testicular ischemia-reperfusion injury in rats.Asian journal of andrologyArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeKorean red ginseng (KRG) is a potent antioxidant and a free radical scavenger. This study was designed to determine whether KRG could protect against dysfunction and oxidative stress induced by torsion-detorsion injury in rat testis. MATERIALS AND
methodsSix-week-old male Sprague-Dawley rats were randomly divided into four groups: a sham-operated control group (C), a sham-operated and KRG-treated group (K), a 2 hours torsion and detorsion group (T), and a 2 hours torsion and detorsion and KRG-treated group (T+K). We measured testis weight and hormone levels and reactive oxygen species (ROS) from the left renal vein. Superoxide generation was measured on the basis of lucigenin-enhanced chemiluminescence in testis tissue.
resultsTesticular weight was significantly higher in the T+K group than in the T group; however, there were no significant differences in hormone levels between the 4 groups. The mean level of ROS and superoxide production was significantly higher in the T group than in the C group, whereas administration of KRG attenuated this increase. Upon histologic evaluation, the T group was found to have cellular disarray, a lack of cellular cohesiveness, degenerative changes in the germinal cells, and less distinct changes in the seminiferous tubules, whereas the T+K group had a germinal epithelial layer that appeared nearly normal.
conclusionsThe present study demonstrated that KRG recovered the testis dysfunction in the rat testis by suppressing superoxide production.
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