ArticleChest2011
CURB-65 pneumonia severity assessment adapted for electronic decision support.
Article in Chest, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America.American journal of respiratory and critical care medicine · 2019Guideline
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- Article
- Exploratory association between multimodal AI-derived digital biomarkers and in-hospital mortality in adult patients with pneumonia: A proof-of-concept study.PLOS digital health · 2026Article
- Profound anemia in hospitalized community acquired pneumonia patients is associated with increased mortality and is prevalent in all patients' age-groups. a retrospective analysis of 15,121 patients.BMC infectious diseases · 2025Article
- Clinical Scores of Peripartum Patients Admitted to Maternity Wards Compared to the ICU: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Machine Learning Models for Differentiating Causes of Dyspnea in Emergency Department Patients: A Retrospective Study.Journal of multidisciplinary healthcare · 2025Article
- Cyclosporin A as an Add-On Therapy to a Corticosteroid-Based Background Treatment in Patients with COVID-19: A Multicenter, Randomized Clinical Trial.Journal of clinical medicine · 2024Article
- Pneumonia diagnosis performance in the emergency department: a mixed-methods study about clinicians' experiences and exploration of individual differences and response to diagnostic performance feedback.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- ICU Utilization After Implementation of Minor Severe Pneumonia Criteria in Real-Time Electronic Clinical Decision Support.Critical care medicine · 2024Article
- Diagnosis and Treatment of Pneumonia in Urgent Care Clinics: Opportunities for Improving Care.Open forum infectious diseases · 2024Article
- Limitations in the use of automated mental status detection for clinical decision support.International journal of medical informatics · 2023Article
- Rapid Assessment of COVID-19 Mortality Risk with GASS Classifiers.Biomedicines · 2023Article
- How and when to manage respiratory infections out of hospital.European respiratory review : an official journal of the European Respiratory Society · 2022Review
- Clinical Implication ofInfection & chemotherapy · 2022Article
- Genetic-based adaptive momentum estimation for predicting mortality risk factors for COVID-19 patients using deep learning.International journal of imaging systems and technology · 2022Article
- Automated Pulmonary Embolism Risk Assessment Using the Wells Criteria: Validation Study.JMIR formative research · 2022Article
- Influence of overweight and obesity on the mortality of hospitalized patients with community-acquired pneumonia.World journal of clinical cases · 2022Article
- Deploying an Electronic Clinical Decision Support Tool for Diagnosis and Treatment of Pneumonia Into Rural and Critical Access Hospitals: Utilization, Effect on Processes of Care, and Clinician Satisfaction.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2022Article
- Statistical Analysis and Machine Learning Prediction of Disease Outcomes for COVID-19 and Pneumonia Patients.Frontiers in cellular and infection microbiology · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundAccurate severity assessment is crucial to the initial management of community-acquired pneumonia (CAP). The CURB-65 (confusion, uremia, respiratory rate, BP, age ≥ 65 years) score contains data that are entered routinely in electronic medical records and are, thus, electronically calculable. The aim of this study was to determine whether an electronically generated severity estimate using CURB-65 elements as continuous and weighted variables better predicts 30-day mortality than the traditional CURB-65.
methodsIn a retrospective cohort study at a US university-affiliated community teaching hospital, we identified 2,069 patients aged 18 years or older with CAP confirmed by radiographic findings in the ED. CURB-65 elements were extracted from the electronic medical record, and 30-day mortality was identified with the Utah Population Database. Performance of a severity prediction model using continuous and weighted CURB-65 variables was compared with the traditional CURB-65 in the US derivation population and validated in the original 1,048 patients from the CURB-65 international derivation study.
resultsThe traditional, binary CURB-65 score predicted mortality in the US cohort with an area under the curve (AUC) of 0.82. Our severity prediction model generated from continuous, weighted CURB-65 elements was superior to the traditional CURB-65, with an out-of-bag AUC of 0.86 (P < .001). This finding was validated in the international database, with an AUC of 0.85 for the electronic model compared with 0.80 for the traditional CURB-65 (P = .01).
conclusionsUsing CURB-65 elements as continuous and weighted data improved prediction of 30-day mortality and could be used as a real-time, electronic decision support tool or to adjust outcomes by severity when comparing processes of care.
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