Evidence map›Paper›PMID 21163610›Full record

ArticleJournal of vascular surgery2011

Socioeconomic and hospital-related predictors of amputation for critical limb ischemia.

Antonia J Henry, Nathanael D Hevelone, Michael Belkin, Louis L Nguyen

Abstract read
In one paragraph

Article in Journal of vascular surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Racial and Socioeconomic Health Disparities in Peripheral Artery Disease.Journal of the American Heart Association · 2024
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16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Antonia J HenryDivision of Vascular and Endovascular Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02115, USA.
Nathanael D Hevelone
Michael Belkin
Louis L Nguyen

Funding

THE POLITICAL ECONOMY OF PUBLIC HEALTH, 1870-1940P01AG010120 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI COSTA, DORA L · 1992 to 2018
$31.5M
HARVARD-LONGWOOD RESEARCH TRAINING IN VASCULAR SURGERYT32HL007734 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI FERRAN, CHRISTIANE, LOGERFO, FRANK W · 1993 to 2023
$10.5M
Percutaneous Treatment of Claudication: The Role of Diabetes and InflammationK23HL084386 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI NGUYEN, LOUIS LOC · 2006 to 2010
$797k
CHOLESTEROL METABOLISMK06HL000734 · NHLBI · WISTAR INSTITUTE · PI KRITCHEVSKY, DAVID · 1985 to 2006
$241k
NHLBI NIH HHS K06 HL000734NHLBI NIH HHS K23 HL084386NHLBI NIH HHS L30 HL090383NHLBI NIH HHS T32 HL00734NHLBI NIH HHS T32 HL007734NIA NIH HHS P01 AG010120
6 · The paper itself

Abstract

objectiveDisparities in limb salvage procedures may be driven by socioeconomic status (SES) and access to high-volume hospitals. We sought to identify SES factors associated with major amputation in the setting of critical limb ischemia (CLI).

methodsThe 2003-2007 Nationwide Inpatient Sample was queried for discharges containing lower extremity revascularization (LER) or major amputation and chronic CLI (N = 958,120). The Elixhauser method was used to adjust for comorbidities. Significant predictors in bivariate logistic regression were entered into a multivariate logistic regression for the dependent variable of amputation vs LER.

resultsOverall, 24.2% of CLI patients underwent amputation. Significant differences were seen between both groups in bivariate and multivariate analysis of SES factors, including race, income, and insurance status. Lower-income patients were more likely to be treated at low-LER-volume institutions (odds ratio [OR], 1.74; P < .001). Patients at higher-LER-volume centers (OR, 15.16; P <.001) admitted electively (OR, 2.19; P < .001) and evaluated with diagnostic imaging (OR, 10.63; P < .001) were more likely to receive LER.

conclusionsAfter controlling for comorbidities, minority patients, those with lower SES, and patients with Medicaid were more likely receive amputation for CLI in low-volume hospitals. Addressing SES and hospital factors may reduce amputation rates for CLI.

Indexed as

Socioeconomic FactorsAgedAmputation, SurgicalDiagnostic ImagingElective Surgical ProceduresFemaleHealthcare DisparitiesHospital Bed CapacityHospitalsHumansInsurance, HealthIschemiaLimb SalvageLogistic ModelsLower ExtremityMale

Identifiers

PMID21163610
PMCPMC3282120

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.