Evidence map›Paper›PMID 21163592›Full record

Trial reportDrug and alcohol dependence2011

Cigarette smoking and short-term addiction treatment outcome.

P T Harrell, I D Montoya, K L Preston, L M Juliano, D A Gorelick

Abstract readClinical Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Smoking and opioid detoxification: behavioral changes and response to treatment.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013
    Trial
  2. Article
  3. Factors associated with the successful completion of a substance rehabilitation programme at a psychiatric training hospital.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2020
    Article
  4. Cigarette Cue Attentional Bias in Cocaine-Smoking and Non-Cocaine-Using Cigarette Smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016
    Article
  5. Article
  6. Article
  7. Cigarette smoking and quit attempts among injection drug users in Tijuana, Mexico.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

P T HarrellIntramural Research Program, National Institute on Drug Abuse/NIH, Baltimore, MD 21224, USA.
I D Montoya
K L Preston
L M Juliano
D A Gorelick
American University · USNational Institute on Drug Abuse · US

Funding

Prevention of Relapse in AddictionZIADA000536 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI PRESTON, KENZIE · 2009 to 2018
$9.5M
Evaluation Of Treatments Of Opioid And Cocaine DependenceZIADA000175 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI PRESTON, KENZIE · 2009 to 2016
$7.4M
Development Of New Pharmacologic And Biologic Treatments For Drug DependenceZIADA000240 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI HUESTIS, MARILYN A · 2009 to 2013
$894k
Psychological And Methodological Issues In Substance Abuse Treatment/researchZIADA000234 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI PRESTON, KENZIE · 2009 to 2010
$546k
Identification Of Factors Associated With Response To Drugs And TreatmentZIADA000241 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI GORELICK, DAVID ALAN · 2009 to 2010
$515k
Intramural NIH HHS ZIA DA000241
6 · The paper itself

Abstract

Cigarette smoking is common among patients in cocaine and opioid dependence treatment, and may influence treatment outcome. We addressed this issue in a secondary analysis of data from an outpatient clinical trial of buprenorphine treatment for concurrent cocaine and opioid dependence (13 weeks, N=200). The association between cigarette smoking (lifetime cigarette smoking status, number of cigarettes smoked per day prior to study entry) and short-term treatment outcome (% of urine samples positive for cocaine or opioids, treatment retention) was evaluated with analysis of covariance, bivariate correlations, and multivariate linear regression. Nicotine-dependent smokers (66% of participants) had a significantly higher percentage of cocaine-positive urine samples than non-smokers (12% of participants) (76% vs. 62%), but did not differ in percentage of opioid-positive urine samples or treatment retention. Number of cigarettes smoked per day at baseline was positively associated with percentage of cocaine-positive urine samples, even after controlling for baseline sociodemographic and drug use characteristics, but was not significantly associated with percentage of opioid-positive urine samples or treatment retention. These results suggest that cigarette smoking is associated with poorer short-term outcome of outpatient treatment for cocaine dependence, but perhaps not of concurrent opioid dependence, and support the importance of offering smoking cessation treatment to cocaine-dependent patients.

Indexed as

AdultAnalgesics, OpioidBehavior, AddictiveBuprenorphineCocaine-Related DisordersFemaleHumansMaleMiddle AgedSmokingSubstance-Related DisordersTime FactorsTobacco Use DisorderTreatment OutcomeAnalgesics, OpioidBuprenorphine

Identifiers

PMID21163592
PMCPMC3080462
OpenAlexW2060138312

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.