Evidence map›Paper›PMID 21162410›Full record

ArticleAmerican journal of disaster medicine

Evidence-based point-of-care tests and device designs for disaster preparedness.

T Keith Brock, Daniel M Mecozzi, Stephanie Sumner, Gerald J Kost

Abstract read
In one paragraph

Article in American journal of disaster medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

T Keith BrockUC Davis-LLNL Point-of-Care Technologies Center, Department of Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, USA.
Daniel M Mecozzi
Stephanie Sumner
Gerald J Kost
University of California, Davis · US

Funding

Rapid Multipathogen Detection for POCT and National Diaster ReadinessU54EB007959 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KOST, GERALD JOSEPH · 2007 to 2011
$8.5M
NIBIB NIH HHS U54 EB007959
6 · The paper itself

Abstract

objectivesTo define pathogen tests and device specifications needed for emerging point-of-care (POC) technologies used in disasters.

designSurveys included multiple-choice and ranking questions. Multiple-choice questions were analyzed with the chi2 test for goodness-of-fit and the binomial distribution test. Rankings were scored and compared using analysis of variance and Tukey's multiple comparison test.

participantsDisaster care experts on the editorial boards of the American Journal of Disaster Medicine and the Disaster Medicine and Public Health Preparedness, and the readers of the POC Journal.

resultsVibrio cholera and Staphylococcus aureus were top-ranked pathogens for testing in disaster settings. Respondents felt that disaster response teams should be equipped with pandemic infectious disease tests for novel 2009 H1N1 and avian H5N1 influenza (disaster care, p < 0.05; POC, p < 0.01). In disaster settings, respondents preferred self-contained test cassettes (disaster care, p < 0.05; POC, p < 0.001) for direct blood sampling (POC, p < 0.01) and disposal of biological waste (disaster care, p < 0.05; POC, p < 0.001). Multiplex testing performed at the POC was preferred in urgent care and emergency room settings.

conclusionsEvidence-based needs assessment identifies pathogen detection priorities in disaster care scenarios, in which Vibrio cholera, methicillin-sensitive and methicillin-resistant Staphylococcus aureus, and Escherichia coli ranked the highest. POC testing should incorporate setting-specific design criteria such as safe disposable cassettes and direct blood sampling at the site of care.

Indexed as

Disaster PlanningPoint-of-Care SystemsAnalysis of VarianceChi-Square DistributionCholeraClinical Laboratory TechniquesCommunicable DiseasesDisaster MedicineEscherichia coli InfectionsEvidence-Based MedicineHumansInfluenza A Virus, H1N2 SubtypeInfluenza, HumanMedical Waste DisposalStaphylococcal InfectionsStatistics, NonparametricMedical Waste Disposal

Identifiers

PMID21162410
PMCPMC3074570
OpenAlexW2217170609

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.