ReviewMolecular neurobiology2011
Neuroglial roots of neurodegenerative diseases?
Review in Molecular neurobiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 74 citations in OpenAlex.
- Article
- Visual Tract Degradation in Bilateral Normal-Tension Glaucoma-Cortical Thickness Maps and Volumetric Study of Visual Pathway Areas.Journal of clinical medicine · 2022Article
- Utilizing 3D Arterial Spin Labeling to Identify Cerebrovascular Leak and Glymphatic Obstruction in Neurodegenerative Disease.Diagnostics (Basel, Switzerland) · 2021Review
- Article
- Novel MRI Techniques Identifying Vascular Leak and Paravascular Flow Reduction in Early Alzheimer Disease.Biomedicines · 2020Review
- Early and late neuropathological features of meningoencephalitis associated with Maraba virus infection.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020Article
- Mitochondrial Dysfunction, Neurogenesis, and Epigenetics: Putative Implications for Amyotrophic Lateral Sclerosis Neurodegeneration and Treatment.Frontiers in neuroscience · 2020Review
- Article
- Astrocytic changes with aging and Alzheimer's disease-type pathology in chimpanzees.The Journal of comparative neurology · 2019Article
- The contribution of S100B to the glioprotective effects of valproic and arundic acids.Iranian journal of basic medical sciences · 2019Article
- Hepatic encephalopathy: Lessons from preclinical studies.World journal of hepatology · 2019Review
- Astroglia in Alzheimer's Disease.Advances in experimental medicine and biology · 2019Review
- SIRT1 facilitates amyloid beta peptide degradation by upregulating lysosome number in primary astrocytes.Neural regeneration research · 2018Article
- Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease.Redox biology · 2017Article
- Observational
- Astrocytes mediated the nootropic and neurotrophic effects of Sarsasapogenin-AA13 via upregulating brain-derived neurotrophic factor.American journal of translational research · 2017Article
- The Antioxidant Effects of Thymoquinone in Activated BV-2 Murine Microglial Cells.Neurochemical research · 2016Article
- Targeted gene transfer to the brain via the delivery of brain-penetrating DNA nanoparticles with focused ultrasound.Journal of controlled release : official journal of the Controlled Release Society · 2016Article
- Astrogliopathology in neurological, neurodevelopmental and psychiatric disorders.Neurobiology of disease · 2016Article
- Why are astrocytes important?Neurochemical research · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuroglia is critically important for controlling the brain homeostasis and for mounting the brain defence against pathological insults. Here, we overview recent data about the role of neuroglia in various types of neurodegenerative diseases (Alzheimer's disease, Parkinson's disease, fronto-temporal dementia, Wernicke encephalopathy, amyotrophic lateral sclerosis and immunodeficiency virus-1-associated dementia). In all these forms of neurodegeneration, astroglia undergoes complex morphological and functional changes. The early and mid-term stages of neurodegenerative processes, and specifically of Alzheimer's disease, are associated with generalised atrophy of astroglia, whereas the later stages are characterised with an astrogliosis and microglial activation linked to neuropathological lesions such as senile plaques. Atrophic changes in astroglia may contribute to the initial cognitive deficits due to reduced glial synaptic coverage and decreased neuroprotection.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.