Evidence map›Paper›PMID 21161405›Full record

ArticleMolecular biology reports2011

Quantitative analysis of expression of six BmGST genes in silkworm, Bombyx mori.

Guo-Dong Zhao, Yi-Ling Zhang, Rui-Na Gao, Rui-Xian Wang, Ting Zhang, Bing Li, Yi Zhang, Chang-de Lu, Wei-de Shen, Zheng-Guo Wei

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Article in Molecular biology reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Guo-Dong ZhaoPre-Clinical Medical and Biological Science College, Soochow University, No. 199 Renai Road, Dushu Lake Higher Education Town, Suzhou Industrial Park, Suzhou 215123, Jiangsu, China.
Yi-Ling Zhang
Rui-Na Gao
Rui-Xian Wang
Ting Zhang
Bing Li
Yi Zhang
Chang-de Lu
Wei-de Shen
Zheng-Guo Wei
Soochow University · CNCenter for Excellence in Molecular Cell Science · CNInstitute of Modern Physics · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glutathione S-transferases (GSTs) are a multifunctional super gene family, some of which play an important role in insecticide resistance. In this research, we used a real-time quantitative RT-PCR method, and a novel strategy, to measure the transcriptional level per gene copy using an exogenous RNA reference and DNA reference. The transcription levels of six BmGST genes in different tissues of fifth instar Bombyx mori larvae and their responses to insecticide and fluoride were investigated. The results show different levels and patterns of expression of the different BmGSTs in the various tissues observed. The BmGSTs can be induced by insecticide and fluoride, but their responses to each are different. The results of this research are helpful in studying the tissue-specific expression of BmGSTs in Bombyx mori, and in developing new pesticide resistant silkworm varieties.

Indexed as

Gene Expression Regulation, EnzymologicAnimalsBombyxDigestive SystemFat BodyGene DosageGene Expression ProfilingGenes, InsectGlutathione TransferaseInsecticidesLarvaMalpighian TubulesOrgan SpecificitySodium FluorideTranscription, GeneticGlutathione TransferaseInsecticidesSodium Fluoride

Identifiers

PMID21161405
OpenAlexW1981406357

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.