ReviewJournal of neural transmission (Vienna, Austria : 1996)2011
Migraine is a neuronal disease.
Review in Journal of neural transmission (Vienna, Austria : 1996), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- Increased activation of the pregenual anterior cingulate cortex to citalopram challenge in migraine: an fMRI study.BMC neurology · 2019Trial
- The Use of vHIT in the Differential Diagnosis Between Vestibular Migraine and Meniere's Disease: A Systematic Review and Meta-Analysis.Audiology research · 2025Review
- The role of kynurenines in migraine-related neuroimmune pathways.The journal of headache and pain · 2024Review
- Neurotransmitter and tryptophan metabolite concentration changes in the complete Freund's adjuvant model of orofacial pain.The journal of headache and pain · 2020Article
- Are Migraine With and Without Aura Really Different Entities?Frontiers in neurology · 2019Review
- Video head impulse test (vHIT) in migraine dizziness.Journal of otology · 2018Article
- American football and other sports injuries may cause migraine/persistent pain decades later and can be treated successfully with electrical twitch-obtaining intramuscular stimulation (ETOIMS).BMJ innovations · 2017Article
- Inhibitory effect of high-frequency greater occipital nerve electrical stimulation on trigeminovascular nociceptive processing in rats.Journal of neural transmission (Vienna, Austria : 1996) · 2017Article
- Shared genetic risk between migraine and coronary artery disease: A genome-wide analysis of common variants.PloS one · 2017Article
- Prophylactic Drug Treatment of Migraine in Children and Adolescents: An Update.Current pain and headache reports · 2016Review
- Diverse effects of Brilliant Blue G administration in models of trigeminal activation in the rat.Journal of neural transmission (Vienna, Austria : 1996) · 2015Article
- Treatment of Chronic Migraine with OnabotulinumtoxinA: Mode of Action, Efficacy and Safety.Toxins · 2015Review
- Decreased antioxidant status in migraine patients with brain white matter hyperintensities.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2014Article
- Kynurenines and other novel therapeutic strategies in the treatment of dementia.Therapeutic advances in neurological disorders · 2013Article
- A single-point mutation (Ala280Val) in the third intracellular loop alters the signalling properties of the human histamine H₃ receptor stably expressed in CHO-K1 cells.British journal of pharmacology · 2013Article
- Studies on the pathophysiology and genetic basis of migraine.Current genomics · 2013Article
- Gene expression microarray analysis of the spinal trigeminal nucleus in a rat model of migraine with aura.Neural regeneration research · 2012Article
- The effects of phytosomal curcumin supplementation on clinical symptoms, and inflammatory and oxidative stress biomarkers in patients with migraine: A protocol for a randomized double-blind placebo-controlled trial.Avicenna journal of phytomedicineArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Migraine is a common, paroxysmal, highly disabling primary headache disorder with a genetic background. The primary cause and the origin of migraine attacks are enigmatic. Numerous clinical and experimental results suggest that activation of the trigeminal system (TS) is crucial in its pathogenesis, but the primary cause of this activation is not fully understood. Since activation of the peripheral and central arms of the TS might be related to cortical spreading depression and to the activity of distinct brainstem nuclei (e.g. the periaqueductal grey), we conclude that migraine can be explained as an altered function of the neuronal elements of the TS, the brainstem, and the cortex, the centre of this process comprising activation of the TS. In light of our findings and the literature data, therefore, we can assume that migraine is mainly a neuronal disease.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.