Evidence map›Paper›PMID 21161204›Full record

ArticlePediatric radiology2011

Optimized T1- and T2-weighted volumetric brain imaging as a diagnostic tool in very preterm neonates.

Revital Nossin-Manor, Andrew D Chung, Drew Morris, João P Soares-Fernandes, Bejoy Thomas, Hai-Ling M Cheng, Hilary E A Whyte, Margot J Taylor, John G Sled, Manohar M Shroff

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric radiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Revital Nossin-ManorDepartment of Diagnostic Imaging, The Hospital for Sick Children, Neurosciences & Mental Health, Research Institute, 555 University Ave., Toronto, M5G 1X8, Canada. rmanor@phenogenomics.ca
Andrew D Chung
Drew Morris
João P Soares-Fernandes
Bejoy Thomas
Hai-Ling M Cheng
Hilary E A Whyte
Margot J Taylor
John G Sled
Manohar M Shroff
Hospital for Sick Children · CAUniversity of Toronto · CA

Funding

PHS HHS MOP-84399
6 · The paper itself

Abstract

backgroundT1- and T2-W MR sequences used for obtaining diagnostic information and morphometric measurements in the neonatal brain are frequently acquired using different imaging protocols. Optimizing one protocol for obtaining both kinds of information is valuable.

objectiveTo determine whether high-resolution T1- and T2-W volumetric sequences optimized for preterm brain imaging could provide both diagnostic and morphometric value. MATERIALS AND

methodsThirty preterm neonates born between 24 and 32 weeks' gestational age were scanned during the first 2 weeks after birth. T1- and T2-W high-resolution sequences were optimized in terms of signal-to-noise ratio, contrast-to-noise ratio and scan time and compared to conventional spin-echo-based sequences.

resultsNo differences were found between conventional and high-resolution T1-W sequences for diagnostic confidence, image quality and motion artifacts. A preference for conventional over high-resolution T2-W sequences for image quality was observed. High-resolution T1 images provided better delineation of thalamic myelination and the superior temporal sulcus. No differences were found for detection of myelination and sulcation using conventional and high-resolution T2-W images.

conclusionHigh-resolution T1- and T2-W volumetric sequences can be used in clinical MRI in the very preterm brain to provide both diagnostic and morphometric information.

Indexed as

Infant, PrematureBrainFemaleHumansImage EnhancementImaging, Three-DimensionalInfant, NewbornMagnetic Resonance ImagingMaleReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID21161204
OpenAlexW2107609693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.