Evidence map›Paper›PMID 21160930›Full record

ArticleWorld journal of gastrointestinal oncology2010

Three novel NEIL1 promoter polymorphisms in gastric cancer patients.

Masanori Goto, Kazuya Shinmura, Hong Tao, Shoichiro Tsugane, Haruhiko Sugimura

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastrointestinal oncology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Research progress on the role of the NEIL family in cancer.Frontiers in cell and developmental biology · 2025
    Review
  2. Article
  3. Article
  4. Polymorphism of the DNA base excision repair genes in keratoconus.International journal of molecular sciences · 2014
    Article
  5. Base excision repair and cancer.Cancer letters · 2012
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Masanori GotoMasanori Goto, Kazuya Shinmura, Hong Tao, Haruhiko Sugimura, First Department of Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi Ward, Hamamatsu, Shizuoka 431-3192, Japan.
Kazuya Shinmura
Hong Tao
Shoichiro Tsugane
Haruhiko Sugimura
Hamamatsu University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo identify genetic polymorphisms in the promoter region of the human base excision repair gene NEIL1 in gastric cancer patients.

methodsThe NEIL1 promoter region in DNA from 80 Japanese patients with gastric cancer was searched for genetic polymorphisms by polymerase chain reaction-single-strand conformation polymorphism and subsequent sequencing analyses.

resultsThree novel genetic polymorphisms, i.e. c.-3769C>T, c.-3170T>G, and c.-2681TA[8], were identified in the NEIL1 promoter region at an allele frequency of 0.6%, 9.4%, and 4.4%, respectively, in Japanese gastric cancer patients.

conclusionThree NEIL1 promoter polymorphisms detected in this study may be of importance in gastric carcinogenesis.

Indexed as

Base excision repairGastric cancerGenetic polymorphismNEIL1

Identifiers

PMID21160930
PMCPMC2999164
OpenAlexW2031286371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.