Evidence map›Paper›PMID 21159945›Full record

ArticleJournal of clinical microbiology2011

High proportion of wrongly identified methicillin-resistant Staphylococcus aureus carriers by use of a rapid commercial PCR assay due to presence of staphylococcal cassette chromosome element lacking the mecA gene.

Dominique S Blanc, Patrick Basset, Immaculée Nahimana-Tessemo, Katia Jaton, Gilbert Greub, Giorgio Zanetti

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 84 citations in OpenAlex.

  1. Review
  2. Detection of Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2022
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  5. Reliability ofOpen forum infectious diseases · 2020
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  9. Cohort description: The Danish Blood DonorClinical epidemiology · 2019
    Article
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  12. [Advances in diagnostic microbiology : Opportunities and limitations].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2017
    Review
  13. Review
  14. High frequency of occupied attB regions in Norwegian Staphylococcus aureus isolates supports a two-step MRSA screening algorithm.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017
    Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Dominique S BlancHospital Preventive Medicine Service, Institute of Microbiology, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland. dominique.blanc@chuv.ch
Patrick Basset
Immaculée Nahimana-Tessemo
Katia Jaton
Gilbert Greub
Giorgio Zanetti
Institute of Microbiology · CNUniversity of Lausanne · CHUniversity Hospital of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During a 9-month period, 217 patients were newly diagnosed as methicillin-resistant Staphylococcus aureus (MRSA) carriers by using a commercial rapid PCR-based test (GeneXpert). However, no MRSA was recovered by culturing the second swab in 61 of these patients. Further analyses showed that 28 (12.9%) of the patients harbored S. aureus isolates with a staphylococcal cassette chromosome element lacking the mecA gene and were thus incorrectly determined to be MRSA carriers.

Indexed as

False Positive ReactionsBacterial ProteinsBacteriological TechniquesCarrier StateDNA, BacterialHumansMethicillin-Resistant Staphylococcus aureusPenicillin-Binding ProteinsPolymerase Chain ReactionStaphylococcal InfectionsBacterial ProteinsDNA, BacterialmecA protein, Staphylococcus aureusPenicillin-Binding Proteins

Identifiers

PMID21159945
PMCPMC3043509
OpenAlexW2153539422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.