Evidence map›Paper›PMID 21159452›Full record

Trial reportDrug and alcohol dependence2011

Behavioral drug and HIV risk reduction counseling (BDRC) in MMT programs in Wuhan, China: a pilot randomized clinical trial.

M C Chawarski, W Zhou, R S Schottenfeld

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Drug and alcohol dependence, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 23 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 8 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03705143 nacompletednot on this mapstarted 2018, after this paper: background citation

The Behavioral Activation for Chinese Substance Users (C-BA) Research Protocol

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2018 to 2018Enrolled90ConditionsSubstance-Related Disorders, Mood Disorders, Behavioral Activation Treatment, Mental DisordersArmsTreatment as usual, Chinese translated LETS ACT
NCT03721380 nacompletednot on this mapstarted 2012, after this paper: background citation

Efficacy of Drug and Risk Behavior Counseling Intervention Among Injecting Drug Users at Opioid Substitution Treatment

TypeinterventionalSponsorNational Taiwan UniversityRan2012 to 2015Enrolled118ConditionsSubstance Use DisordersArmsTreatment as usual
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 8 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

M C ChawarskiDepartment of Psychiatry, Yale University School of Medicine, 34 Park St., New Haven, CT 06519, USA. marek.chawarski@yale.edu
W Zhou
R S Schottenfeld
Yale University · USWuhan Center for Disease Control and Prevention · CN

Funding

HIV Risk Reduction and Drug Abuse Treatment in MalaysiaR01DA014718 · NIDA · YALE UNIVERSITY · PI SCHOTTENFELD, RICHARD S · 2001 to 2013
$3.6M
Brief Introductory Therapy for Opioid DependenceR01DA013108 · NIDA · YALE UNIVERSITY · PI CHAWARSKI, MAREK C · 1999 to 2006
$1.6M
IMPROVING EFFICACY OF DRUG ABUSE TREATMENTK24DA000445 · NIDA · YALE UNIVERSITY · PI SCHOTTENFELD, RICHARD S · 2000 to 2009
$1.3M
NIDA NIH HHS DA14718-05A1S1NIDA NIH HHS K24 DA000445NIDA NIH HHS K24 DA00445NIDA NIH HHS R01 DA013108NIDA NIH HHS R01 DA014718
6 · The paper itself

Abstract

This pilot clinical trial evaluated whether the efficacy of methadone maintenance treatment (MMT) provided with limited psychosocial services is improved by the addition of manual-guided behavioral drug and HIV risk reduction counseling (BDRC). Heroin dependent individuals (n=37) enrolling in two MMT clinics in Wuhan, China, received standard MMT services, consisting of daily medication at the clinics and infrequent additional services on demand, and were randomly assigned to MMT only (n=17) or MMT with weekly individual BDRC (n=20) for 3 months. Participants were followed for six months from the time of enrollment (3 months active counseling phase and 3 months follow-up while treated with standard MMT). Primary outcome measures included reductions of HIV risk behaviors and illicit opiate use and treatment retention. Participants were 81% male; mean (SD) age 36.7 (7.2) years; there were no significant baseline differences between the two groups. Participants in MMT+BDRC achieved both greater reductions of HIV risk behaviors (p<0.01), as indicated by the scores on a short version of the AIDS Risk Inventory, and of illicit opiate use, as indicated by the proportions of opiate negative test results during the active phase of the study and the follow-up (p<0.001). 83.3% in the MMT+BDRC group and 76.2% in the standard MMT group were still actively participating in MMT at 6 months. Manual-guided behavioral drug and HIV risk reduction counseling is feasible to deliver by the trained MMT nursing personnel and appears to be a promising approach for improving the efficacy of standard MMT services in China.

Indexed as

AdultChinaCounselingFemaleHeroin DependenceHIV InfectionsHIV SeropositivityHumansMaleMethadoneNarcoticsOpiate Substitution TreatmentOpioid-Related DisordersPilot ProjectsRisk Reduction BehaviorRisk-TakingMethadoneNarcotics

Identifiers

PMID21159452
PMCPMC3076517
OpenAlexW2083343730

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.