ReviewInternational wound journal2011
Genetic and epigenetic events in diabetic wound healing.
Review in International wound journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Intensive versus conventional glycaemic control for treating diabetic foot ulcers.The Cochrane database of systematic reviews · 2016Pooled it
- Dipeptidyl peptidase 4 inhibition may facilitate healing of chronic foot ulcers in patients with type 2 diabetes.Experimental diabetes research · 2012Trial
- Beyond the Triad: Uncommon Initial Presentations in Newly Diagnosed Type 2 Diabetes Mellitus.Cureus · 2025Article
- The Potential of Sheep or Camel Milk Constituents to Contribute to Novel Dressings for Diabetic Wounds.International journal of molecular sciences · 2023Review
- Secretome of Adipose-Derived Stem Cells Cultured in Platelet Lysate Improves Migration and Viability of Keratinocytes.International journal of molecular sciences · 2023Article
- Immunomodulatory biomaterials on chemokine signaling in wound healing.Frontiers in pharmacology · 2023Review
- RETRACTED: Design and Evaluation of Solid Lipid Nanoparticles Loaded Topical Gels: Repurpose of Fluoxetine in Diabetic Wound Healing.Gels (Basel, Switzerland) · 2022Article
- Increasing Angiogenesis Factors in Hypoxic Diabetic Wound Conditions by siRNA Delivery: Additive Effect of LbL-Gold Nanocarriers and Desloratadine-Induced Lysosomal Escape.International journal of molecular sciences · 2021Article
- Basics of Epigenetics and Role of Epigenetics in Diabetic Complications.Journal of pharmacy & bioallied sciences · 2021Article
- Intralesional Infiltrations of Cell-Free Filtrates Derived from Human Diabetic Tissues Delay the Healing Process and Recreate Diabetes Histopathological Changes in Healthy Rats.Frontiers in clinical diabetes and healthcare · 2021Article
- One-year safety, healing and amputation rates of Wagner 3-4 diabetic foot ulcers treated with cryopreserved umbilical cord (TTAX01).Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2020Article
- Keratinocyte Function in Normal and Diabetic Wounds and Modulation by FOXO1.Journal of diabetes research · 2020Review
- Cellular Senescence as the Pathogenic Hub of Diabetes-Related Wound Chronicity.Frontiers in endocrinology · 2020Review
- Mesenchymal Stem Cells Coated by the Extracellular Matrix Promote Wound Healing in Diabetic Rats.Stem cells international · 2019Article
- Hesperidin, a plant flavonoid accelerated the cutaneous wound healing in streptozotocin-induced diabetic rats: Role of TGF-ß/Smads and Ang-1/Tie-2 signaling pathways.EXCLI journal · 2018Article
- Plantar pressures are elevated in people with longstanding diabetes-related foot ulcers during follow-up.PloS one · 2017Article
- Diabetic cornea wounds produce significantly weaker electric signals that may contribute to impaired healing.Scientific reports · 2016Article
- High glucose improves healing of periodontal wound by inhibiting proliferation and osteogenetic differentiation of human PDL cells.International wound journal · 2016Article
- Epigenetics in the perioperative period.British journal of pharmacology · 2015Review
- Epigenetic mechanisms in diabetic complications and metabolic memory.Diabetologia · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of the chronic metabolic disorder, diabetes mellitus, is expected to increase in the coming years and worldwide pandemic levels are predicted. Inevitably, this will be accompanied by an increase in the prevalence of diabetic complications, including diabetic foot ulcers. At present, treatment options for diabetic foot ulcers are in many cases insufficient, and progression of the condition results in the requirement for limb amputation in a proportion of patients. To improve therapy, an increase in our understanding of the pathobiology of diabetic complications such as impaired wound healing is necessary. In this review, recent advances in molecular aspects of normal and impaired diabetic wound healing are discussed. Furthermore, investigations of the role of epigenetic processes in the pathogenesis of impaired diabetic wound healing are now emerging. Indeed, epigenetic changes have already been identified as key factors in diabetes and related complications and these are overviewed in this review.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.